Results 51 to 60 of about 89,444 (289)

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Neurological and Musculoskeletal Features of COVID-19: A Systematic Review and Meta-Analysis

Frontiers in Neurology, 2020
Importance: Some of the symptoms of COVID-19 are fever, cough, and breathing difficulty. However, the mechanism of the disease, including some of the symptoms such as the neurological and musculoskeletal symptoms, is still poorly understood.Objective ...
Auwal Abdullahi, Auwal Abdullahi, Sevim Acaroz Candan, Muhammad Aliyu Abba, Muhammad Aliyu Abba, Auwal Hassan Bello, Mansour Abdullah Alshehri, Mansour Abdullah Alshehri, Egwuonwu Afamefuna Victor, Naima Aliyu Umar, Burak Kundakci   +10 more
doaj   +1 more source

A young woman with myalgia [PDF]

Clinical Medicine, 2014
We describe the case of a young female presenting with myalgia, mildly raised creatine kinase and a rash. The discussion emphasises the importance of a systematic approach to muscle symptoms, the value of a detailed hand examination and the importance of magnetic resonance imaging in the investigation of muscular symptoms.
Abarna, Ratnarajah, Brendan, Barber, Yohan, Samarasinghe, Mark, Lloyd   +3 more
openaire   +2 more sources

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Expert Perspective: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

Arthritis &Rheumatology, Accepted Article.
Treat‐to‐target (T2T) has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal T2T framework for adult IIM has not yet been established.
Shiri Keret, Nantakarn Pongtarakulpanit, Rohit Aggarwal   +2 more
wiley   +1 more source

Clinical presentations and co-morbid factors of patients with myofascial pain or myalgia of masticatory muscles [PDF]

Journal of Oral Health and Oral Epidemiology, 2019
BACKGROUND AND AIM: This study was aimed to investigate the clinical presentations and frequencies of co-morbid factors in patients with myofascial pain or myalgia of masticatory muscles.
Goli Chamani, Elham Abbaszadeh, Mohammad Reza Zarei, Robert Merrill Jr, Maryam Rad   +4 more
doaj   +1 more source

Shared and Distinguishing Features of Late‐Onset Rheumatic Diseases Fulfilling Polymyalgia Rheumatica Classification Criteria

Arthritis &Rheumatology, Accepted Article.
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Kerem Abacar, Ala Altaie, Andrew Barr, Sarah L. Mackie, Kulveer Mankia, Dennis McGonagle   +5 more
wiley   +1 more source

Central Nervous System Involvement in the Eosinophilia-Myalgia Syndrome

, 1992
• A patient with eosinophilia-myalgia syndrome developed progressive central nervous system involvement that did not improve despite discontinuation of l-tryptophan therapy. Neurologic impairment was manifested initially by spastic monoparesis, which was
R. A. Bornstein, K. W. Rammohan, J. T. Kissel, Rammohan, Kottil W, J. Lynn, Bornstein, Robert A, Kissel, John T, Lynn, Joanne   +7 more
core   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreationally active men

Frontiers in Sports and Active Living
Extracts derived from Indian frankincense (Boswellia serrata) effectively reduce the pain and swelling associated with osteoarthritis. It is unknown whether the anti-inflammatory and analgesic properties of B.
Dawna Salter, Himana Yalamanchi, Aiswarya Yalamanchi, Amulya Yalamanchi   +3 more
doaj   +1 more source