Results 151 to 160 of about 91,972 (285)
Vox Sanguinis, EarlyView.Abstract Plasma‐derived medicinal products (PDMPs), particularly immunoglobulins (Igs), are essential treatments for numerous diseases, often serving as the primary therapeutic option and playing a critical role in patient care. The human origin of these products, however, can lead to supply constraints due to a lack of plasma collection, market ...
Miriam Belmonte +4 more
wiley +1 more source
Myasthenia Gravis: Pathogenic Effects of Autoantibodies on Neuromuscular Architecture
Cells, 2019 Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ). Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor (AChR), muscle-specific kinase (MuSK), and low-density lipoprotein receptor ...
I. Koneczny, R. Herbst
semanticscholar +1 more source
PLoS ONE, 2013 BackgroundMyasthenia gravis is a disorder of neuromuscular transmission associated with autoantibodies against the nicotinic acetylcholine receptor. We have previously developed a customized protein macroarray comprising 1827 potential human autoantigens,
Anne Becker +8 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract This systematic review summarizes the available evidence on respiratory muscle endurance training involving voluntary isocapnic hyperpnoea among patients with chronic diseases. It includes both randomized and non‐randomized controlled trials implementing this exercise training modality performed either alone or in combination with other ...
Hélène Laurent +3 more
wiley +1 more source
Understanding the burden of refractory myasthenia gravis
Therapeutic Advances in Neurological Disorders, 2019 Myasthenia gravis (MG) is an autoantibody-mediated disease that compromises the acetylcholine receptors or associated structures of the postsynaptic membrane of the neuromuscular junction.
C. Schneider-Gold +3 more
semanticscholar +1 more source
Weighted cart pull: A novel outcome measure for sustained motor function in mice
Experimental Physiology, EarlyView.Abstract Sarcopenia, the pathological age‐related decline in muscle mass and strength, compromises independence and quality of life in older adults. Currently, no effective treatments are available. To enhance translational research using aged mouse models, we developed and validated the weighted cart pull (WCP) as a novel assessment of sustained motor
Charles D. Brennan +12 more
wiley +1 more source
Effect of pregnancy and birth on the course of myasthenia gravis before or after transsternal radical thymectomy [PDF]
, 2017 Objective: Myasthenia gravis (MG) affects women at childbearing age. Therefore, the question arises if these patients should become pregnant and if thymectomy has a positive effect on the course of MG in pregnant patients.
Carboni, Gianluca +4 more
core
Comedications Associated with Immune‐Related Adverse Events from Immune‐Checkpoint Inhibitors
Clinical Pharmacology &Therapeutics, Volume 118, Issue 3, Page 593-599, September 2025.Immune‐checkpoint inhibitors (ICI) have revolutionized cancer treatment but are responsible for various immune‐related adverse events (irAE). The impact of non‐anticancer medications (comedications) on irAE occurrence remains largely unexplored. The objective of this study was to assess comedications associated with an increased reporting of irAE with ...
Léonard Laurent +10 more
wiley +1 more source