Results 291 to 300 of about 75,991 (309)
Some of the next articles are maybe not open access.
The Indian Journal of Pediatrics, 1989
Twelve children with myasthenic symptoms were seen over a period of 6 years. The age of onset of symptoms ranged from 6 months to 9 years. On followup for a mean period of 4.25 years, (longest followup was 9 years) five children went into complete remission of symptoms after treatment with prostigmine; three children responded to prostigmine and ...
openaire +5 more sources
Twelve children with myasthenic symptoms were seen over a period of 6 years. The age of onset of symptoms ranged from 6 months to 9 years. On followup for a mean period of 4.25 years, (longest followup was 9 years) five children went into complete remission of symptoms after treatment with prostigmine; three children responded to prostigmine and ...
openaire +5 more sources
Veterinary Clinics of North America: Small Animal Practice, 1979
Myasthenia gravis is characterized by muscle weakness, which is alleviated by rest and by anticholinesterase drugs. There are two forms of the disease in the dog, acquired and congenital. The acquired form occurs either in young adults, or in older animals that have developed mediastinal tumors. Clinically, there is weakness of the muscles of the limbs,
openaire +3 more sources
Myasthenia gravis is characterized by muscle weakness, which is alleviated by rest and by anticholinesterase drugs. There are two forms of the disease in the dog, acquired and congenital. The acquired form occurs either in young adults, or in older animals that have developed mediastinal tumors. Clinically, there is weakness of the muscles of the limbs,
openaire +3 more sources
The Epidemiology of Myasthenia Gravis
Seminars in Neurology, 1994Abstract: Population‐based studies of the epidemiology of myasthenia gravis (MG) have been conducted for over 50 years. Over that time, there has been a clear trend towards an increase in the reported prevalence of the disease. In recent years, there has also been an interest in determining a reasonably accurate estimate of the number of MG patients ...
openaire +6 more sources
Seminars in Neurology, 2015
Myasthenia gravis is an autoimmune neuromuscular disease caused by antibodies directed against the postsynaptic muscle membrane. The clinical hallmark of the disease is fluctuating and fatigable weakness that affects the ocular muscles (resulting in diplopia and ptosis), the bulbar muscles (causing dysphagia, dysarthria, and dyspnea), and extremity ...
Kelly G, Gwathmey, Ted M, Burns
openaire +2 more sources
Myasthenia gravis is an autoimmune neuromuscular disease caused by antibodies directed against the postsynaptic muscle membrane. The clinical hallmark of the disease is fluctuating and fatigable weakness that affects the ocular muscles (resulting in diplopia and ptosis), the bulbar muscles (causing dysphagia, dysarthria, and dyspnea), and extremity ...
Kelly G, Gwathmey, Ted M, Burns
openaire +2 more sources
Disease-a-Month, 1997
Adult-onset myasthenia gravis is an acquired autoimmune disorder of neuromuscular transmission in which acetylcholine receptor antibodies attack the postsynaptic membrane of the neuromuscular junction. Although the cause of this disease is unknown, the role of immune responses in its pathogenesis is well established.
openaire +2 more sources
Adult-onset myasthenia gravis is an acquired autoimmune disorder of neuromuscular transmission in which acetylcholine receptor antibodies attack the postsynaptic membrane of the neuromuscular junction. Although the cause of this disease is unknown, the role of immune responses in its pathogenesis is well established.
openaire +2 more sources
Clinical Neurology and Neurosurgery, 1981
Myasthenia gravis is a chronic disease characterized by a fluctuating weakness of voluntary muscle, with a preference for the muscles innervated by cranial nerves. The pathophysiological mechanism is a loss of postsynaptic acetylcholine receptors to less than 20-30% so that the safety margin of neuromuscular transmission is lost.
openaire +4 more sources
Myasthenia gravis is a chronic disease characterized by a fluctuating weakness of voluntary muscle, with a preference for the muscles innervated by cranial nerves. The pathophysiological mechanism is a loss of postsynaptic acetylcholine receptors to less than 20-30% so that the safety margin of neuromuscular transmission is lost.
openaire +4 more sources
Current Opinion in Immunology, 1993
The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.
openaire +2 more sources
The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.
openaire +2 more sources