Results 91 to 100 of about 1,519 (167)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

Advanced Science, Volume 13, Issue 22, 17 April 2026.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu   +10 more
wiley   +1 more source

Non-tuberculous mycobacteria isolates from patients with chronic pulmonary disease and no epidemiological relationship show sequence clusters through whole-genome sequencing

Frontiers in Microbiology
ObjectivesThis study aimed to investigate the genomic epidemiology of slow-growing mycobacteria (SGM) isolates from patients with bronchiectasis through whole-genome sequencing (WGS) and assess various bioinformatic tools to establish relationships ...
Marc Rubio, Marc Rubio, Mariana Fernandez-Pittol, Mariana Fernandez-Pittol, Mariana Fernandez-Pittol, Sara Batista, Sara Batista, Sara Batista, Diego Martínez, Lorena San Nicolas, Elena Portell-Buj, Elena Portell-Buj, Elena Portell-Buj, Maria Antònia Busquets, Maria Antònia Busquets, Joan Estelrich, Joan Estelrich, Julian Gonzalez-Martin, Julian Gonzalez-Martin, Julian Gonzalez-Martin, Julian Gonzalez-Martin, Ferran Navarro, Ferran Navarro, Ferran Navarro, Griselda Tudó, Griselda Tudó, Griselda Tudó, Montserrat Garrigó, Montserrat Garrigó, Montserrat Garrigó   +29 more
doaj   +1 more source

Disseminated Mycobacterium chimaera Following Open-Heart Surgery, the Heater–Cooler Unit Worldwide Outbreak: Case Report and Minireview

Frontiers in Medicine, 2020
Invasive cardiovascular infections by Mycobacterium chimaera associated with open-heart surgery have been reported worldwide since 2013. Here, we report a case of a 61 year old man, without any other particular medical background, who underwent cardiac ...
Emmanuel Lecorche, Emmanuel Lecorche, Emmanuel Lecorche, Gauthier Pean de Ponfilly, Faiza Mougari, Faiza Mougari, Faiza Mougari, Hanaa Benmansour, Hanaa Benmansour, Hanaa Benmansour, Elodie Poisnel, Frederic Janvier, Frederic Janvier, Emmanuelle Cambau, Emmanuelle Cambau, Emmanuelle Cambau   +15 more
doaj   +1 more source

Mycobacterium chimaera and chronic meningitis [PDF]

QJM: An International Journal of Medicine, 2020
K, Sharma, M, Sharma, M, Modi, H, Joshi, M, Goyal, A, Sharma, P, Ray, M C, Rowlinson   +7 more
openaire   +2 more sources

Disseminated Mycobacterium chimaera infection successfully treated with a clofazimine-containing regimen and long-term follow-up after discontinuing treatment

IDCases
Mycobacterium chimaera is a slow-growing member of the Mycobacterium avium complex. It can contaminate tap water and has been detected in water tanks of heater-cooler devices used during open-heart surgery.
Takaaki Kobayashi, Bradley Ford, Daniel J. Diekema, Poorani Sekar   +3 more
doaj   +1 more source

Aortic Endograft Infection with Mycobacterium chimaera and Granulicatella adiacens, Switzerland, 2014

Emerging Infectious Diseases, 2018
We describe an aortic endograft infection caused by Mycobacterium chimaera and Granulicatella adiacens, successfully treated with prolonged antimicrobial drug therapy after complete explantation of the infected endoprosthesis and extra-anatomical ...
Andreas Plate, Thomas A. Kohl, Peter M. Keller, Sabine Majer, Rosamaria Fulchini, Carol Strahm, Cristoforo Medugno, Zoran Rancic, Lars Husmann, Hugo Sax, Stefan Niemann, Barbara Hasse   +11 more
doaj   +1 more source

The Global Outbreak of M. chimaera Infection Following Cardiac Surgery: Another Piece of the Puzzle

Pathogens
Invasive cases of Mycobacterium chimaera have been found in Europe, and beyond, and have been associated with the use of heater–cooler units necessary to regulate the temperature of blood in extracorporeal circulation during cardiac surgery, mostly due ...
Savina Ditommaso, Gabriele Memoli, Francesca Anselmi, Ivan Molineris, Carla Maria Zotti, Monica Giacomuzzi   +5 more
doaj   +1 more source

RETROSPECTIVE ANALYSIS OF SLOVENIAN MYCOBACTERIUM AVIUM COMPLEX AND MYCOBACTERIUM ABSCESSUS COMPLEX ISOLATES AND MOLECULAR RESISTANCE PROFILE

Инфекция и иммунитет, 2018
. Mycobacteria belonging to Mycobacterium (M.) avium complex (MAC) and M. abscessus complex (MABSC) are the most frequent causes of mycobacteriosis in the world.
S. Truden, M. Žolnir-Dovč, E. Sodja, M. Starčič Erjavec   +3 more
doaj   +1 more source

Search for new therapeutic options for the uncommon pathogen Mycobacterium chimaera: an open drug discovery approach

, 2022
Background Mycobacterium chimaera is a slowly growing non-tuberculous mycobacterium associated with outbreaks of fatal infections in patients after cardiac surgery, and it is increasingly being detected in patients with chronic lung conditions.
Emad Salehi (16290230), Daire Cantillon (4464985), Aaron Goff (16039727), Simon Waddell (4462816), Katy Fidler (4462336), Stuart Taylor (678359), Simon Stoneham (16281245)   +6 more
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