Reemergence of Mycobacterium chimaera in Heater–Cooler Units despite Intensified Cleaning and Disinfection Protocol [PDF]
Invasive Mycobacterium chimaera infections after open-heart surgery have been reported internationally. These devastating infections result from aerosols generated by contaminated heater–cooler units used with extracorporeal circulation during surgery ...
Peter W. Schreiber +12 more
doaj +2 more sources
Background Mycobacterium chimaera is a recently described species within the Mycobacterium avium complex. Its pathogenicity in respiratory tract infection remains disputed.
Rolain Jean-Marc +5 more
doaj +2 more sources
Genomic Analysis of Cardiac Surgery–Associated Mycobacterium chimaera Infections, United States
A surgical heater–cooler unit has been implicated as the source for Mycobacterium chimaera infections among cardiac surgery patients in several countries. We isolated M. chimaera from heater–cooler units and patient infections in the United States. Whole-
Nabeeh A. Hasan +13 more
doaj +2 more sources
A Case of Cavitary Mycobacterium chimaera. [PDF]
Mycobacterium chimaera is a nontuberculous mycobacterium typically associated with heater-cooler units used in cardiac bypass procedures and is usually of low virulence. Here we present a patient with advanced Mycobacterium chimaera infection without typical risk factors.
Robinson B, Chaudhri M, Miskoff JA.
europepmc +3 more sources
Transmission of Mycobacterium chimaera from Heater–Cooler Units during Cardiac Surgery despite an Ultraclean Air Ventilation System [PDF]
Heater–cooler units (HCUs) were recently identified as a source of Mycobacterium chimaera causing surgical site infections. We investigated transmission of this bacterium from HCUs to the surgical field by using a thermic anemometer and particle counter,
Rami Sommerstein +5 more
doaj +2 more sources
Etymologia: Mycobacterium chimaera [PDF]
Ronnie Henry
doaj +2 more sources
Mycobacterium chimaera Genomics With Regard to Epidemiological and Clinical Investigations Conducted for an Open Chest Postsurgical Mycobacterium chimaera Infection Outbreak. [PDF]
Abstract Background Postsurgical infections due to Mycobacterium chimaera appeared as a novel nosocomial threat in 2015, with a worldwide outbreak due to contaminated heater-cooler units used in open chest surgery.
Lecorche E +11 more
europepmc +5 more sources
Pharmacologic Management of Mycobacterium chimaera Infections: A Primer for Clinicians. [PDF]
Abstract Mycobacterium chimaera, a member of the Mycobacterium avium complex, can cause infections in individuals after open heart surgery due to contaminated heater-cooler units. The diagnosis can be challenging, as the incubation period can be quite variable, and symptoms are nonspecific.
Mason M +5 more
europepmc +3 more sources
Searching for new therapeutic options for the uncommon pathogen Mycobacterium chimaera: an open drug discovery approach. [PDF]
BACKGROUND: Mycobacterium chimaera is a slowly growing non-tuberculous mycobacterium associated with outbreaks of fatal infections in patients after cardiac surgery, and it is increasingly being detected in patients with chronic lung conditions.
Cantillon D +6 more
europepmc +2 more sources
Drug susceptibility distributions of Mycobacterium chimaera and other non-tuberculous mycobacteria. [PDF]
Recent outbreaks of cardiac surgery-associated Mycobacterium chimaera infections have highlighted the importance of species differentiation within the Mycobacterium avium complex and pointed to a lack of antibiotic susceptibility data for M.
Schulthess B +4 more
europepmc +2 more sources

