Results 61 to 70 of about 1,266 (156)

A single-center experience with microbiologic surveillance of LivaNova 3T heater-cooler devices (HCDs)

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: The global outbreak of Mycobacterium chimaera infections associated with HCDs resulted in new maintenance recommendations. Since 2018, HCDs have been disinfected according to instructions for use (IFU), including twice-monthly bleach ...
Scott Curry   +4 more
doaj   +1 more source

Contact Effect of a Methylobacterium sp. Extract on Biofilm of a Mycobacterium chimaera Strain Isolated from a 3T Heater-Cooler System

open access: yesAntibiotics, 2020
Mycobacterium chimaera is an opportunistic slowly growing non-tuberculous mycobacteriumof increasing importance due to the outbreak of cases associated with contaminated 3T heater-cooler device (HCD) extracorporeal membrane oxygenator (ECMO).
Inés Pradal   +4 more
doaj   +1 more source

Nontuberculous Mycobacterial Lung Disease in the Patients with Cystic Fibrosis—A Challenging Diagnostic Problem

open access: yesDiagnostics, 2022
Background: Cystic fibrosis (CF) is an autosomal, recessive genetic disorder, caused by a mutation in the cystic fibrosis transmembrane conductance receptor regulator (CFTR) gene.
Dorota Wyrostkiewicz   +6 more
doaj   +1 more source

Bacteriomes, cryptic forms and evolution of a common wireworm pest species, Hypnoidus bicolor

open access: yesInsect Molecular Biology, EarlyView.
Wireworms are important agricultural pests, including Hypnoidus bicolor in the Canadian Prairies. Parthenogenetic and sexual populations of H. bicolor appear associated with different molecular clades. Bacterial community composition and structure were influenced by developmental stage, sampling location and host genetics.
Ivan Drahun   +5 more
wiley   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

open access: yesImmunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Plant NAOGAT (ArgJ) Structure Reveals Mechanism of Ornithine Biosynthesis, Preference for Acetylornithine and Susceptibility to Mangotoxin

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Arginine metabolism in plants is targeted by phytopathogens such as Pseudomonas syringae strains, which produce toxins that affect enzymes of plant arginine metabolism, causing devastating infections in crops. In this work, the structural and functional properties of plant N‐acetylornithine glutamate acetyltransferase (NAOGAT), the key ...
Maciej Nielipinski   +3 more
wiley   +1 more source

Rapid detection of invasive Mycobacterium chimaera disease via a novel plasma-based next-generation sequencing test

open access: yesBMC Infectious Diseases, 2019
Background There is an ongoing outbreak of Mycobacterium chimaera infections among patients exposed to contaminated heater-cooler devices used during cardiac surgery. Recognition of M.
Jim Nomura   +8 more
doaj   +1 more source

Strawberry micropropagation simplifies endomicrobiome and highlights potential for in vitro biotization with beneficial rhizobacteria

open access: yesPlant Biology, EarlyView.
Prolonged in vitro micropropagation reshaped the strawberry endomicrobiome, reducing bacterial diversity and community complexity. Biotization with selected plant growth‐promoting bacteria partially compensated for these changes by improving plant performance and acclimatization, supporting microbiome‐assisted approaches for tissue culture systems ...
A. M. G. Sepúlveda   +6 more
wiley   +1 more source

Complete Genome Sequence of Mycobacterium chimaera Strain AH16

open access: yesGenome Announcements, 2016
ABSTRACT Mycobacterium chimaera is a nontuberculous mycobacterial species that causes cardiovascular, pulmonary, and postsurgical infections. Here, we report the first complete genome sequence of M. chimaera .
Hasan, Nabeeh A.   +6 more
openaire   +2 more sources

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