Lung organoids as a human system for Mycobacteria infection modeling and drug testing
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza +4 more
wiley +1 more source
High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study [PDF]
© 2016 Sridhar et al.Background: Long-term outcomes in non-HIV immunocompromised patients with disseminated Mycobacterium avium complex (dMAC) infections are unknown and the need for post-treatment secondary prophylaxis against MAC is uncertain in this ...
Chan, JFW +9 more
core +1 more source
MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections
Nontuberculous mycobacterial (NTM) pulmonary infections are emerging as a global health problem and pose a threat to susceptible individuals with structural or functional lung conditions such as cystic fibrosis, chronic obstructive pulmonary disease and ...
Wei Li +8 more
semanticscholar +1 more source
Sex Differences in Lung Immunity
ABSTRACT Biological sex has a significant impact on how the immune system develops and responds to foreign and self‐antigens. Sex differences exist in innate and adaptive immune cells, both at homeostasis and in the context of infection and inflammatory diseases such as asthma, cancer, and autoimmune disorders.
Franz Puttur, Clare M. Lloyd
wiley +1 more source
Mycobacterium genavense invading the bone marrow in a HIV‐positive patient
Key Clinical Message Nontuberculous mycobacteria infrequently cause disseminated infections in immunocompetent hosts. However, they are increasingly being recognized in immunocompromised patients.
Christianne Bourlon +2 more
doaj +1 more source
Uveitis with occult choroiditis due to Mycobacterium kansasii: limitations of interferon-gamma release assay (IGRA) tests (case report and mini-review on ocular non-tuberculous mycobacteria and IGRA cross-reactivity) [PDF]
Ocular tuberculosis is difficult to diagnose but should be suspected when uveitis fails to respond to inflammation suppressive therapy. Interferon-gamma release assays (IGRAs) represent a substantial help to diagnose suspected ocular tuberculosis ...
Herbort, Carl +2 more
core
Review article: Mycobacterium marinum infection of the hand and wrist. [PDF]
Misdiagnosis and delayed treatment of Mycobacterium marinum infection is common because of its diverse manifestations. This leads to inappropriate use of antimicrobials, extension of the infection from the skin to the tenosynovium, and a poor prognosis ...
Cheung, JP, Fung, B, Ip, WY, Wong, SS
core +1 more source
Mycobacterium marinum (M. marinum) is a slowly growing nontuberculous mycobacterium. The incidence of M. marinum infections in Denmark is unknown. We conducted a retrospective nationwide study including all culture confirmed cases of M. marinum from 2004
I. Holden +5 more
semanticscholar +1 more source
Mycobacterium smegmatis Skin Infection Following Cosmetic Procedures: Report of Two Cases
Caroline J Wang,1 Yinggai Song,2,3 Tingting Li,1 Jian Hu,1 Xue Chen,1 Houmin Li1 1Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Dermatology, Peking University First Hospital, Beijing ...
Wang CJ +5 more
doaj
Tuberculosis in a Psychiatric Hospital in the state of Goiás, Brazil [PDF]
OBJECTIVE: To investigate the prevalence of infection, disease and eventual institutional outbreak of tuberculosis in a psychiatric hospital using the PPD test, as well as testing for mycobacteria in material collected from the respiratory tree and using
Costa, Hindenburg Cruvinel Guimarães Da +3 more
core +2 more sources

