Proposing a two-step Decision Support System (TPIS) based on Stacked ensemble classifier for early and low cost (step-1) and final (step-2) differential diagnosis of Mycobacterium Tuberculosis from non-tuberculosis Pneumonia [PDF]
Background: Mycobacterium Tuberculosis (TB) is an infectious bacterial disease presenting similar symptoms to pneumonia; therefore, differentiating between TB and pneumonia is challenging. Therefore, the main aim of this study is proposing an automatic method for differential diagnosis of TB from Pneumonia.
arxiv
Borderline Lepromatous Leprosy With Type 1 Reaction: A Challenging Diagnostic Case
ABSTRACT Borderline lepromatous leprosy with Type 1 reaction poses significant diagnostic challenges due to overlapping clinical features. Early recognition and differentiation are crucial, especially in endemic regions like Mexico, to ensure prompt, appropriate management and prevent complications.
Polanco Llanes Alondra Saray+5 more
wiley +1 more source
Miniaturised Spotter-Compatible Multicapillary Stamping Tool for Microarray Printing [PDF]
Novel microstamping tool for microarray printing is proposed. The tool is capable to spot up to 127 droplets of different solutions in single touch. It is easily compatible with commercially available microarray spotters. The tool is based on multichannel funnel with polypropylene capillaries inserted into its channels. Superior flexibility is achieved
arxiv
A hanseníase relaciona-se à formação de grande variedade de lesões cutâneas, desde manchas, pápulas, placas e nódulos, até infiltração difusa, dependendo da resposta imune do indivíduo.
Antônio Renê Diógenes de Sousa+4 more
doaj +1 more source
'Perfectly' curvilinear profiles for binding as determined by ITC may in fact be multiphasic [PDF]
In a structural analysis of the proteasome activator PafE in Mycobacterium tuberculosis, the binding of the activator or shorter constructs to the 20S proteasome core particle (20S CP) or derivatives was measured by isothermal titration calorimetry (Bai et al. Proc Natl Acad Sci USA 113: E1983-E1992. 2016).
arxiv
FUNDAMENTOS: Ainda é de grande importância a hanseníase como problema de Saúde Pública no Brasil, devido a sua alta endemicidade. OBJETIVO: Determinar as principais características dessa enfermidade na cidade de Recife no ano de 2002.
Sylvia Lemos Hinrichsen+5 more
doaj +1 more source
Dapsone resistance inMycobacterium leprae
The folP1 gene of Mycobacterium leprae, which encodes dihydropteroate synthase (DHPS), was studied for the presence of mutations associated with resistance to dapsone (DDS). When the folP1 of several DDS-resistant clinical isolates of M. leprae were sequenced, two missense mutations were identified.
D L Williams, Thomas P. Gillis
openaire +3 more sources
Biodegradation of 2-ethylhexyl nitrate (2-EHN) by Mycobacterium austroafricanum IFP 2173 [PDF]
2-Ethyhexyl nitrate (2-EHN) is a major additive of fuel which is used to comply with the cetane number of diesel. Because of its wide use and possible accidental release, 2-EHN is a potential pollutant of the environment. In this study, Mycobacterium austroafricanum IFP 2173 was selected among several strains as the best 2-EHN degrader.
arxiv
On the impact of Masking and Blocking Hypotheses for measuring efficacy of new tuberculosis vaccines [PDF]
Over the past 60 years, the Mycobacterium bovis bacille Calmette-Gu\'erin (BCG) has been used worldwide to prevent tuberculosis (TB). However, BCG has shown a very variable efficacy in different trials, showing a wide range of protection in adults against pulmonary TB.
arxiv
Estudos sobre a Lepra: II. Tentativas de cultura do Mycobacterium Leprae: (Coccothrix Leprae, Lutz, 1886), isolamento de um actinomyces de um Leproma: O Actinomyces Lepromatis, n. sp. (Amostra Hilda) [PDF]
H. C. de Souza-Araújo
openalex +1 more source