Results 101 to 110 of about 187,712 (288)

Visibly Enlarged Feeder Nerves in Hansen's Disease: A Diagnostic Beacon

JEADV Clinical Practice, EarlyView.
Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Prakriti Lamichhane   +3 more
wiley   +1 more source

Serological Evidence of Soil‐Transmitted Helminth Infections as a Potential Risk for Severity in Leprosy Patients

Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.
ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira, Augusto César Parreiras de Jesus, Ramayana Morais de Medeiros Brito, Jordânia Costa‐Pinto, Tatyane Martins Cirilo, José Bryan Rihs, Marcelo Eduardo Cardozo, Lilian Lacerda Bueno, Luisa Mourão Dias Magalhães, Ricardo Toshio Fujiwara   +9 more
wiley   +1 more source

The role of red squirrels in leprosy dynamics in the United Kingdom: a critical review

One Health
In the United Kingdom, the declining population of the red squirrel, the acknowledged historical reservoir for zoonotic Mycobacterium leprae leprosy, is thought to have been behind the decline in leprosy.
S. Souguel, T. Oueslati, G. Grine, M. Drancourt   +3 more
doaj   +1 more source

Our Impressive Immune System: More Than a Defense [PDF]

, 2014
Most likely the immune system was put into place in the original human body design. We know from Exodus 20:11 and other verses that God completed His work of creation in six days.
Conrad, Jason, Gillen, Alan L.
core   +1 more source

Description of a novel adhesin of Mycobacterium avium subsp. paratuberculosis [PDF]

, 2014
The binding and ingestion of Mycobacterium avium subsp. paratuberculosis (MAP) by host cells are fibronectin (FN) dependent. In several species of mycobacteria, a specific family of proteins allows the attachment and internalization of these bacteria by ...
Echeverria Valencia, Gabriela Fernanda, Fernández, Marisa Mariel, Gioffré, Andrea Karina, Malchiodi, Emilio Luis, Mon, Maria Laura, Romano, Maria Isabel, Romasanta, Pablo Nicolas, Santangelo, María de la Paz, Viale, Mariana Noelia   +8 more
core   +1 more source

Mycobacterium leprae-Infected Macrophages Preferentially Primed Regulatory T Cell Responses and Was Associated with Lepromatous Leprosy

PLoS Neglected Tropical Diseases, 2016
Background The persistence of Mycobacterium leprae (M. leprae) infection is largely dependent on the types of host immune responses being induced. Macrophage, a crucial modulator of innate and adaptive immune responses, could be directly infected by M ...
De-gang Yang, Tiejun Shui, Jake W. Miranda, D. Gilson, Zhengyu Song, Jia Chen, C. Shi, Jianyu Zhu, Jun Yang, Z. Jing   +9 more
semanticscholar   +1 more source

Persistent Facial Nodules in an Elderly Patient

JEADV Clinical Practice, EarlyView.
Qian Ding, Qin‐Si Liu, Heng‐Guang Zhao   +2 more
wiley   +1 more source

Nucleotide‐Binding Oligomerization Domain 2 in Signaling, Immunity, and Mycobacterial Infection

Immunity, Inflammation and Disease, Volume 13, Issue 9, September 2025.
NOD2 is a cytoplasmic receptor that detects bacterial components and plays key roles in immune surveillance, but it also has diverse noncanonical immunomodulatory functions beyond pathogen recognition. This review explores NOD2's activation mechanisms, classical and nonclassical immune roles, and its impact on mycobacterial defense, highlighting the ...
Yi Wang, Zihao Mi, Hong Liu, Furen Zhang
wiley   +1 more source

MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]

, 2012
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
A Freitag, A Gevorgyan, A Mithani, Albert Gevorgyan, AM Feist, AM Feist, AM Feist, Andrzej M. Kierzek, AP Burgard, BA Pfeifer, CS Henry, D Nagrath, DC Alexander, DC Stevens, EM Paradise, Eriko Takano, FC Lee, H Ikeda, I Thiele, J Gonzalez-Lergier, J Romero, J Schellenberger, JD Orth, JL Adrio, JP Brooks, JS Edwards, K Nieselt, K Yanai, LM Blank, M DeJongh, M Durot, M Kanehisa, M Latendresse, MA Fischbach, MA Oberhardt, MA Oberhardt, MA Oberhardt, Marnix H. Medema, MH Medema, MH Medema, MH Medema, MH Medema, MT Alam, MT Alam, MW Covert, N Scherr, ND Price, ND Price, NE Lewis, Piotr Zakrzewski, PR Ives, R Breitling, R Schuetz, Rainer Breitling, SA Becker, SD Bentley, Stephen S. Fong, TD Vo, TY Kim, XQ Zhao   +59 more
core   +6 more sources

Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae

PLoS Neglected Tropical Diseases, 2018
Background The immune system depends on effector pathways to eliminate invading pathogens from the host in vivo. Macrophages (MΦ) of the innate immune system are armed with vitamin D-dependent antimicrobial responses to kill intracellular microbes ...
Elliot W. Kim, Rosane M. B. Teles, Salem Haile, Philip T Liu, R. Modlin   +4 more
semanticscholar   +1 more source