Nitazoxanide is active against Mycobacterium leprae
PLOS ONE, 2017 Nitazoxanide (NTZ) is an anti-parasitic drug that also has activity against bacteria, including Mycobacterium tuberculosis. Our data using both radiorespirometry and live-dead staining in vitro demonstrate that NTZ similarly has bactericidal against M. leprae. Further, gavage of M.
Mai Ann Bailey +5 more
openaire +5 more sources
Brazilian Journal of Infectious Diseases, 2017 Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection.
Alexandre Casimiro de Macedo +4 more
doaj
A Study of Quantitative Correlations Between Crucial Bio-markers and the Optimal Drug Regimen of Type-I Lepra Reaction [PDF]
arXivLeprosy (Hansen's) is a disease caused by Mycobacterium leprae. This disease slowly leads to occurrence of leprae reactions which mainly damage peripheral nervous system which cause loss of organs. We can prevent occurring leprae reactions by monitoring the bio-markers involved in it.
arxiv
Mycobacterium leprae in Mice: Minimal Infectious Dose, Relationship Between Staining Quality and Infectivity, and Effect of Cortisone [PDF]
, 1965 Charles C. Shepard, Dorothy H. McRae
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Zoonotic Leprosy in the Southeastern United States
Emerging Infectious Diseases, 2015 Nine-banded armadillos (Dasypus novemcinctus) are naturally infected with Mycobacterium leprae and have been implicated in zoonotic transmission of leprosy.
Rahul Sharma +10 more
doaj +1 more source
Use of 3,4-Dihydroxyphenylalanine Oxidation in the Identification of Mycobacterium leprae [PDF]
, 1966 K Prabhakaran, W. F. Kirchheimer
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ELECTRON MICROSCOPE STUDY OF MYCOBACTERIUM LEPRAE AND ITS ENVIRONMENT IN A VESICULAR LEPROUS LESION [PDF]
, 1962 T Imaeda, J Convit
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A Data Mining Approach to the Diagnosis of Tuberculosis by Cascading Clustering and Classification [PDF]
Journal of computing, volume 3, issue 4,April 2011, ISSN 2151-9617, 2011 In this paper, a methodology for the automated detection and classification of Tuberculosis(TB) is presented. Tuberculosis is a disease caused by mycobacterium which spreads through the air and attacks low immune bodies easily. Our methodology is based on clustering and classification that classifies TB into two categories, Pulmonary Tuberculosis(PTB ...
arxiv
Predictive Comparative QSAR analysis of Sulfathiazole Analogues as Mycobacterium Tuberculosis H37RV Inhabitors [PDF]
published 2012, 2014 Antitubercular activity of Sulfathiazole Derivitives series were subjected to Quantitative Structure Activity Relationship (QSAR) Analysis with an attempt to derive and understand a correlation between the Biologically Activity as dependent variable and various descriptors as independent variables. QSAR models generated using 28 compounds.
arxiv
Learning modular structures from network data and node variables [PDF]
arXiv, 2014 A standard technique for understanding underlying dependency structures among a set of variables posits a shared conditional probability distribution for the variables measured on individuals within a group. This approach is often referred to as module networks, where individuals are represented by nodes in a network, groups are termed modules, and the
arxiv