Results 111 to 120 of about 187,712 (288)
Abstract Objectives We investigated the prevalence of anti‐phenolic glycolipid‐I (PGL‐I) IgM antibodies among temporarily unfit blood donors at the Pará State Blood Bank (HEMOPA), located in the Amazon region of northern Brazil. Using an arbitrary high cutoff for optical density (OD ≥0.750) in ELISA, a subset of donors was invited for clinical ...
Erika Vanessa Oliveira Jorge +12 more
wiley +1 more source
Leprosy is a chronic infection of the skin and nerves caused by Mycobacterium leprae and the newly discovered Mycobacterium lepromatosis. Human leprosy has been documented for millennia in ancient cultures. Recent genomic studies of worldwide M.
Xiang Y Han, Francisco J Silva
doaj +1 more source
Advances in Proteomics of Mycobacterium leprae [PDF]
AbstractAlthough Mycobacterium leprae was the first bacterial pathogen identified causing human disease, it remains one of the few that is non‐cultivable. Understanding the biology of M. leprae is one of the primary challenges in current leprosy research.
O. Parkash, B. P. Singh
openaire +3 more sources
A rare case of lepromatous leprosy in Germany
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Roman Saternus +8 more
wiley +1 more source
The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans , in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs +6 more
wiley +1 more source
Mycobacterium leprae alters classical activation of human monocytes in vitro
BackgroundMacrophages play a central role in the pathogenesis of leprosy, caused by Mycobacterium leprae. The polarized clinical presentations in leprosy are associated with differential immune activation.
D. Fallows +3 more
semanticscholar +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Variation of TTC Repeat Pattern in the Dna of Mycobacterium Leprae Isolates Obtained From Archeological Bones and Leprosy Patients From East Nusa Tenggara [PDF]
The existence of leprosy or kusta or Morbus Hansen or Hansens disease has been known for years, including in Indonesia. Starting from the discovery of Mycobacterium leprae isolates from ancient bone (about 1.000 years B.C), the archaeological excavations
Adriaty, D. (Dinar) +6 more
core +1 more source
Rab32 restriction of intracellular bacterial pathogens [PDF]
Experiments in the authors’ laboratory are supported by the Wellcome Trust (grant no. 109680/Z/15/Z), the Royal Society (grant no. RG150386), and Tenovus Scotland (grant no. G14/19) to SS.
Rofe, Adam +2 more
core +1 more source
Lenvatinib‐Associated Non‐Tuberculous Mycobacterial Pulmonary Disease: A Case Report
This article presents a case of a hepatocellular carcinoma patient who developed pulmonary NTM infection after long‐term lenvatinib therapy, as detected by next‐generation sequencing (NGS). Symptoms improved and follow‐up CT showed resolution after discontinuation of lenvatinib for 2 months.
Qian Wang +3 more
wiley +1 more source

