Results 121 to 130 of about 187,712 (288)

A Systematic Review of Immunological Studies of Erythema Nodosum Leprosum. [PDF]

open access: yes, 2017
Erythema nodosum leprosum (ENL) is a painful inflammatory complication of leprosy occurring in 50% of lepromatous leprosy patients and 5-10% of borderline lepromatous patients.
Abalos   +228 more
core   +1 more source

Evaluating the Benefits and Limits of Multiple Displacement Amplification With Whole‐Genome Oxford Nanopore Sequencing

open access: yesMolecular Ecology Resources, Volume 25, Issue 6, August 2025.
ABSTRACT Multiple displacement amplification (MDA) outperforms conventional PCR in long fragment and whole‐genome amplification, making it attractive to couple MDA with long‐read sequencing of samples with limited quantities of DNA to obtain improved genome assemblies.
Fiifi Agyabeng‐Dadzie   +10 more
wiley   +1 more source

Evidence for symmetric chromosomal inversions around the replication origin in bacteria. [PDF]

open access: yes, 2000
BackgroundWhole-genome comparisons can provide great insight into many aspects of biology. Until recently, however, comparisons were mainly possible only between distantly related species.
Eisen, JA   +3 more
core   +1 more source

Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae

open access: yesMemórias do Instituto Oswaldo Cruz, 2017
BACKGROUND The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy.
Maria Luisa Bezerra de Macedo Arraes   +8 more
semanticscholar   +1 more source

Increased CD8dim and Decreased CD8bright T Cells as Immunological Signature for Multibacilary Leprosy Patients

open access: yesImmunology, Volume 175, Issue 4, Page 444-452, August 2025.
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, manifests in a spectrum of clinical forms and severity. This study investigated the percentage of CD8+ T cells and their subpopulations (CD8bright and CD8dim T cells) in leprosy patients stratified by clinical forms, bacterial load, and age.
Yuri Scheidegger de Castro   +7 more
wiley   +1 more source

Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery

open access: yesEmerging Microbes and Infections, 2019
Of the more than 190 distinct species of Mycobacterium genus, many are economically and clinically important pathogens of humans or animals. Among those mycobacteria that infect humans, three species namely Mycobacterium tuberculosis (causative agent of ...
Vaishali P. Waman   +7 more
doaj   +1 more source

Experimental Infection of Rhodnius prolixus (Hemiptera, Triatominae) with Mycobacterium leprae Indicates Potential for Leprosy Transmission

open access: yesPLoS ONE, 2016
Leprosy is a chronic dermato-neurological disease caused by infection with Mycobacterium leprae. In 2013 almost 200,000 new cases of leprosy were detected around the world.
A. S. Neumann   +13 more
semanticscholar   +1 more source

A novel approach for feline sporotrichosis pathogen detection based on loop‐mediated isothermal amplification

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 474-484, August 2025.
Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Steffanie Amadei   +6 more
wiley   +1 more source

Recent advances in nontuberculous mycobacterial lung infections [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Nontuberculous mycobacteria (NTM) are members of the Mycobacterium genus other than Mycobacterium tuberculosis complex and Mycobacterium leprae. NTM are widely distributed in the environment and are increasingly recognized as causes of chronic lung ...
David Horne, Shawn Skerrett
doaj   +1 more source

Presence of viable Mycobacterium leprae in environmental specimens around houses of leprosy patients

open access: yesIndian Journal of Medical Microbiology, 2016
Purpose: Leprosy is a chronic systemic infectious disease caused by Mycobacterium leprae, one of the first organisms to be established as the cause for disease in humans.
R. Turankar   +5 more
semanticscholar   +1 more source

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