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The truncated hemoglobin from Mycobacterium leprae

Biochemical and Biophysical Research Communications, 2002
Truncated hemoglobins (trHb's) form a family of low molecular weight O2 binding hemoproteins distributed in eubacteria, protozoa, and plants. TrHb's branch in a distinct clade within the hemoglobin (Hb) superfamily. A unique globin gene has recently been identified from the complete genome sequence of Mycobacterium leprae that is predicted to encode a ...
VISCA P   +8 more
openaire   +6 more sources

Mycobacterium leprae

2002
Publisher Summary Mycobacterium leprae (M. leprae) is one of the first organisms to be established as the cause of diseases in humans. In spite of this, it is the least understood of any bacterium of medical importance. All mycobacteria are difficult to work with; the pathogens have to be handled in high-containment facilities, their unusual cell ...
openaire   +2 more sources

Nitric Oxide and Mycobacterium leprae Pathogenicity

IUBMB Life, 2002
AbstractLeprosy is an old, still dreaded infectious disease caused by the obligate intracellular bacterium Mycobacterium leprae . During the infectious process, M. leprae is faced with the host macrophagic environment, where the oxidative stress and NO release, combined with low pH, low pO 2, and high pCO 2, contribute to limit the growth of the ...
VISCA, PAOLO   +4 more
openaire   +5 more sources

Properties of lysophospholipase in Mycobacterium leprae

Journal of Basic Microbiology, 1996
AbstractLysophospholipids are key intermediates in the metabolism of phospholipids. Cytoplasmic membranes of both eukaryotes and prokaryotes are made of phospholipid bilayers. Phospholipases are activated during phagocytosis. Lysophospholipids generated by phospholipase A2 or A1 degrade cell membranes and can cause cell lysis.
K. Prabhakaran   +2 more
openaire   +3 more sources

Mycobacterium leprae

2015
Mycobacterium leprae is the aetiologic agent of leprosy affecting the skin and peripheral nerves. The infection is currently found in over 100 countries often located in high-burden areas against a low-burden background of cases. Clinical manifestations are varied and reflect the host’s immune response to the bacteria. M.
openaire   +2 more sources

Antigenic Analysis of Mycobacterium leprae

Scandinavian Journal of Immunology, 1979
About twenty distinct antigenic components have been demonstrated in Mycubacterium leprae (M. leprae) by crossed immunoelectrophoresis against a rabbit antiserum produced by immunization with concentrated M, leprae antigen. This system allows a more detailed analysis of the antigenic relationship between M, leprae and other mycobacteria and a better ...
O. Closs, R. N. Mshana, Morten Harboe
openaire   +3 more sources

The growth of Mycobacterium leprae in snakes

Canadian Journal of Microbiology, 1974
Mycobacterium leprae, obtained from a human case of lepromatous leprosy, was successfully grown in newborn snakes, within 5 to 6 weeks, and it was transferred from snake to snake, upon intramuscular injection.
J. B. G. Kwapinski   +2 more
openaire   +3 more sources

Biochemical studies on Mycobacterium leprae

Journal of Basic Microbiology, 1986
AbstractVery little information is available on the basic biology of Mycobacterium leprae. It is not known why the organism fails to grow in bacteriological media or in cell cultures and why it has an unusual predilection for certain tissues in the human host where cells derived from the neural crest occur (e. g.
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Mycobacterium leprae

2021
Peter M Lydyard   +6 more
openaire   +1 more source

Mycobacterium leprae Immunostaining Pitfall

The American Journal of Dermatopathology, 2022
Harsimran, Kaur   +2 more
openaire   +2 more sources

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