Results 51 to 60 of about 640 (103)

Determinación de la persistencia y diagnóstico tardío de lepra en el Valle del Cauca de 2010 a 2016

Revista Facultad Nacional de Salud Pública, 2021
Objetivo: Describir la frecuencia, las características clínicodemográficas y los factores relacionados con el retraso diagnóstico, con tratamientos incompletos y con el desarrollo de discapacidad entre el ingreso y el egreso de pacientes inscritos en
Adriana Marcela Rivas Mina, Alejandra Chantré Cusi, Jennifer Santa Yepes, Diana Marcela Hoyos Ocampo, Robinson Pacheco, Beatriz E. Ferro   +5 more
doaj   +1 more source

Nucleotide‐Binding Oligomerization Domain 2 in Signaling, Immunity, and Mycobacterial Infection

Immunity, Inflammation and Disease, Volume 13, Issue 9, September 2025.
NOD2 is a cytoplasmic receptor that detects bacterial components and plays key roles in immune surveillance, but it also has diverse noncanonical immunomodulatory functions beyond pathogen recognition. This review explores NOD2's activation mechanisms, classical and nonclassical immune roles, and its impact on mycobacterial defense, highlighting the ...
Yi Wang, Zihao Mi, Hong Liu, Furen Zhang
wiley   +1 more source

Leprosy in blood donors

Tropical Medicine &International Health, Volume 30, Issue 9, Page 1018-1022, September 2025.
Abstract Objectives We investigated the prevalence of anti‐phenolic glycolipid‐I (PGL‐I) IgM antibodies among temporarily unfit blood donors at the Pará State Blood Bank (HEMOPA), located in the Amazon region of northern Brazil. Using an arbitrary high cutoff for optical density (OD ≥0.750) in ELISA, a subset of donors was invited for clinical ...
Erika Vanessa Oliveira Jorge, Angélica Rita Gobbo, Izabelle Laissa Viana Costa, Raquel Carvalho Bouth, Sâmela Miranda da Silva, Ana Caroline Cunha Messias, Josafá Gonçalves Barreto, Patrícia Fagundes da Costa, Pablo Diego do Carmo Pinto, Moises Batista da Silva, John Stewart Spencer, Maurício Koury Palmeira, Claudio Guedes Salgado   +12 more
wiley   +1 more source

Advances in the Immunology and Genetics of Leprosy

Frontiers in Immunology, 2020
Leprosy, a disease caused by the intracellular parasite Mycobacterium leprae or Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a stigmatized disease even now.
Zihao Mi, Hong Liu, Furen Zhang
doaj   +1 more source

The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review

Zoonoses and Public Health, Volume 72, Issue 6, Page 485-500, September 2025.
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans , in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs, Bridgette McNamara, Sarah Hayman, Kim Blasdell, Eugene Athan, Daniel P. O'Brien, Michael Muleme   +6 more
wiley   +1 more source

Leprosy in Refugees and Migrants in Italy and a Literature Review of Cases Reported in Europe between 2009 and 2018

Microorganisms, 2020
Leprosy is a chronic neglected infectious disease that affects over 200,000 people each year and causes disabilities in more than four million people in Asia, Africa, and Latin America.
Anna Beltrame, Gianfranco Barabino, Yiran Wei, Andrea Clapasson, Pierantonio Orza, Francesca Perandin, Chiara Piubelli, Geraldo Badona Monteiro, Silvia Stefania Longoni, Paola Rodari, Silvia Duranti, Ronaldo Silva, Veronica Andrea Fittipaldo, Zeno Bisoffi   +13 more
doaj   +1 more source

Next-generation sequencing-assisted diagnosis of a case of leprosy misdiagnosed as erythema multiforme

Annals of Clinical Microbiology and Antimicrobials, 2022
Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae or Mycobacterium lepromatosis that is mainly transmitted through droplets from the nose and mouth of untreated patients.
Yanfang Zhang, Xuezhong Lei, Jiajie Lu
doaj   +1 more source

Beyond Elimination: Unveiling Leprosy Cases in Far West Nepal

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Leprosy, one of the Neglected Tropical Diseases (NTDs), can be diagnosed based on any of its three characteristics: a hypopigmented or reddish skin patch with sensory loss, thickened peripheral nerves with sensory impairment, and a positive skin smear for acid‐fast bacilli (AFB).
Smriti Lama Thing, Deepak Subedi, Anita Tamang Waiba, Neha Bista, Apsara Hamal, Monika Gurung   +5 more
wiley   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, Volume 599, Issue 9, Page 1203-1221, May 2025.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

L‐PRF in extra‐oral wound care

Periodontology 2000, Volume 97, Issue 1, Page 342-362, February 2025.
Abstract Leukocyte‐ and platelet‐rich fibrin (L‐PRF), a by‐product of centrifuged autologous whole blood, contains high concentrations of platelets, leukocytes, and fibrin (the latter spontaneously creating a strong 3‐D network (a membrane)). L‐PRF membranes possess several characteristics essential in wound healing, including a barrier function, an ...
Nelson Pinto, Jize Yu, Sushil Koirala, Carlos Fernando Mourão, Catherine Andrade, Enrico Rescigno, Yelka Zamora, Diego Pinto, Marc Quirynen   +8 more
wiley   +1 more source