Results 51 to 60 of about 109,859 (140)

The Predictive Role of Biomarkers for Leprosy Prophylaxis in Contacts of Patients Who Are Indices of the Disease: A Systematic Review of the Literature

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Leprosy continues to be an important public health problem, particularly in endemic regions such as Brazil, India, and Indonesia. Household contacts of multibacillary (MB) patients represent a high‐risk group for subclinical infection due to prolonged exposure and high bacillary load.
Luiza Raquel Tapajós Figueira, Marcos Jessé Abrahão Silva, Lucas Vinicius Moraes da Silva, Rebecca Lobato Marinho, Keitty Anne Silva Neves, Thiago Augusto Ferreira dos Anjos, Lilian Cristina Santos Sinfronio da Silva, Daniele Melo Sardinha, Everaldina Cordeiro dos Santos, Luana Nepomuceno Gondim Costa Lima, Mirella Giovarelli   +10 more
wiley   +1 more source

Lepra Bubalorum, a Potential Reservoir of Mycobacterium leprae

Frontiers in Microbiology, 2021
In 1926, a mycobacterial skin disease was observed in water buffaloes by researchers in Indonesia. The disease was designated as skin tuberculosis, though it was hypothesized that it might be a form of leprosy or a leprosy-like disease.
William R. Faber, Henk Menke, Victor Rutten, Victor Rutten, Toine Pieters   +4 more
doaj   +1 more source

Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health

Journal of Applied Ecology, Volume 62, Issue 11, Page 2894-2913, November 2025.
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley   +1 more source

Reservoirs and transmission routes of leprosy; A systematic review.

PLoS Neglected Tropical Diseases, 2020
Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy bacilli cause similar pathologic conditions.
Thomas Ploemacher, William R Faber, Henk Menke, Victor Rutten, Toine Pieters   +4 more
doaj   +1 more source

Determinación de la persistencia y diagnóstico tardío de lepra en el Valle del Cauca de 2010 a 2016

Revista Facultad Nacional de Salud Pública, 2021
Objetivo: Describir la frecuencia, las características clínicodemográficas y los factores relacionados con el retraso diagnóstico, con tratamientos incompletos y con el desarrollo de discapacidad entre el ingreso y el egreso de pacientes inscritos en
Adriana Marcela Rivas Mina, Alejandra Chantré Cusi, Jennifer Santa Yepes, Diana Marcela Hoyos Ocampo, Robinson Pacheco, Beatriz E. Ferro   +5 more
doaj   +1 more source

Serological Evidence of Soil‐Transmitted Helminth Infections as a Potential Risk for Severity in Leprosy Patients

Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.
ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira, Augusto César Parreiras de Jesus, Ramayana Morais de Medeiros Brito, Jordânia Costa‐Pinto, Tatyane Martins Cirilo, José Bryan Rihs, Marcelo Eduardo Cardozo, Lilian Lacerda Bueno, Luisa Mourão Dias Magalhães, Ricardo Toshio Fujiwara   +9 more
wiley   +1 more source

Mycobacterium tuberculosis Beijing genotype. [PDF]

, 2003
Molecular epidemiologic studies of strains of Mycobacterium tuberculosis are currently conducted worldwide. The genetically distinct Beijing family of strains has been associated with large outbreaks of tuberculosis, increased virulence, and multidrug ...
Lillebaek, Troels, Judith R. Glynn, Andersen, Åse B., Troels Lillebaek, Glynn, Judith R., Kremer, Kristin, Åse B. Andersen, Asger Dirksen, Kristin Kremer, Andersen, Ase B, Glynn, Judith R, Dirksen, Asger   +11 more
core   +1 more source

Nucleotide‐Binding Oligomerization Domain 2 in Signaling, Immunity, and Mycobacterial Infection

Immunity, Inflammation and Disease, Volume 13, Issue 9, September 2025.
NOD2 is a cytoplasmic receptor that detects bacterial components and plays key roles in immune surveillance, but it also has diverse noncanonical immunomodulatory functions beyond pathogen recognition. This review explores NOD2's activation mechanisms, classical and nonclassical immune roles, and its impact on mycobacterial defense, highlighting the ...
Yi Wang, Zihao Mi, Hong Liu, Furen Zhang
wiley   +1 more source

Advances in the Immunology and Genetics of Leprosy

Frontiers in Immunology, 2020
Leprosy, a disease caused by the intracellular parasite Mycobacterium leprae or Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a stigmatized disease even now.
Zihao Mi, Hong Liu, Furen Zhang
doaj   +1 more source

Leprosy in blood donors

Tropical Medicine &International Health, Volume 30, Issue 9, Page 1018-1022, September 2025.
Abstract Objectives We investigated the prevalence of anti‐phenolic glycolipid‐I (PGL‐I) IgM antibodies among temporarily unfit blood donors at the Pará State Blood Bank (HEMOPA), located in the Amazon region of northern Brazil. Using an arbitrary high cutoff for optical density (OD ≥0.750) in ELISA, a subset of donors was invited for clinical ...
Erika Vanessa Oliveira Jorge, Angélica Rita Gobbo, Izabelle Laissa Viana Costa, Raquel Carvalho Bouth, Sâmela Miranda da Silva, Ana Caroline Cunha Messias, Josafá Gonçalves Barreto, Patrícia Fagundes da Costa, Pablo Diego do Carmo Pinto, Moises Batista da Silva, John Stewart Spencer, Maurício Koury Palmeira, Claudio Guedes Salgado   +12 more
wiley   +1 more source