Results 241 to 250 of about 239,747 (314)

Evaluation of alternative antimicrobial strategies in high-performance pigs for managing endemic Mycoplasma hyopneumoniae populations. [PDF]

Trop Anim Health Prod
Nagae RY, Barcellos DESN, Takeuti KL, Mellagi APG, Cé TRM, Cavazinni N, Kunrath C, Scher A, Wolf J, Bortolozzo FP, Ulguim RDR.   +10 more
europepmc   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Successful diagnosis and treatment of mycoplasma peritoneal dialysis peritonitis using metagenomic next-generation sequencing: one case report

Linchuang shenzangbing zazhi
Qian Yang
doaj   +1 more source

<i>Isolation</i>, identification, biological characteristics analysis, and inactivated vaccine research of <i>Mycoplasma canis</i> from respiratory tract of dogs in Yunnan Province, China. [PDF]

Front Vet Sci
Kou M, Xu T, Wang Y, Xie J, Huang J, Xin Y, Chen C, Fan Q, Mao A, Miao H.   +9 more
europepmc   +1 more source

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

Advanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao, Dalin Chen, Ziyi Zhang, Jingxuan Ren, Chengcheng Zhao, Shengfang Wang, Mengyu Shang, Dawei Jiang, Yinuo Li, Su'an Tang, Kai Li, Xiaohui Zhang, Xiaogang Wang   +12 more
wiley   +1 more source

Bovine Respiratory Mycoplasmas and the Commensal-Pathogen Continuum: A Systematic Review of Vaccines and Diagnostic Approaches. [PDF]

Animals (Basel)
Werid GM, Ibrahim YM, Wubshet AK, Aleri JW, Hemmatzadeh F, Petrovski KR.   +5 more
europepmc   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Identification of Mycoplasma bovis directly from bronchoalveolar lavage fluid with MALDI-TOF MS [PDF]

, 2019
Bokma, Jade, Boyen, Filip, Deprez, Piet, Haesebrouck, Freddy, Pardon, Bart, Van Driessche, Laura   +5 more
core  

Identification and Antimicrobial Susceptibility of <i>Mycoplasma capricolum</i> subsp. <i>capripneumoniae</i> Isolates from China During 2024-2025. [PDF]

Vet Sci
Cheng Z, Yang L, Wei Y, Zhang W, Wu Y, Liu M, Si F, Li C, Feng Z, Li W.   +9 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source