Results 11 to 20 of about 3,499 (179)

A RNase H2-Linked TaqMan-MGB Quantitative Real-Time PCR Assay for Differential Detection of <i>Mycoplasma hyopneumoniae</i> Live-Attenuated Vaccine Strains. [PDF]

Transbound Emerg Dis
Mycoplasma hyopneumoniae (M. hyopneumoniae), the etiological agent of porcine enzootic pneumonia, is one of the most prevalent and economically significant respiratory pathogens in the swine industry. Vaccination constitutes a primary strategy for controlling M. hyopneumoniae infections.
Peng K, Wei Y, Wu Y, Yuan T, Li J, Jiang P, Xie Q, Feng Z.   +7 more
europepmc   +2 more sources

Field Evaluation of a Novel Combined Vaccine Against Porcine Circovirus Types 2a/d, Mycoplasma hyopneumoniae and Mycoplasma hyorhinis With an Emphasis on Growth Performance. [PDF]

Vet Med Sci
A field trial on three commercial farms evaluated a combined vaccine targeting PCV2a/d, Mycoplasma hyopneumoniae, and Mycoplasma hyorhinis. Vaccinated pigs showed improved average daily weight gain, stronger immune responses against these pathogens, and significantly reduced viral and mycoplasmal loads and lesion severity, supporting its efficacy under
Suh J, Ham S, Na H, Kang I, Oh T, You Y, Park B, Chae C.   +7 more
europepmc   +2 more sources

Genotype diversity of Mycoplasma Hyopneumoniae in Chinese swine herds based on multilocus sequence typing

BMC Veterinary Research, 2021
Background Between 2018 and 2020, 989 clinical specimens from pigs showing clinical signs of a variety of swine diseases in 27 provinces in China were sampled and submitted for further testing.
Hui Zhang, Yuanyuan Wang, Lu Gao, Yan Wang, Rong Wei   +4 more
doaj   +1 more source

Intrinsic terminators in Mycoplasma hyopneumoniae transcription [PDF]

BMC Genomics, 2015
Mycoplasma hyopneumoniae, an important pathogen of swine, exhibits a low guanine and cytosine (GC) content genome. M. hyopneumoniae genome is organised in long transcriptional units and promoter sequences have been mapped upstream of all transcription units. These analysis provided insights into the gene organisation and transcription initiation at the
Fritsch, Tiago Ebert, Siqueira, Franciele Maboni, Schrank, Irene Silveira   +2 more
openaire   +2 more sources

Mycoplasma hyopneumoniae evades complement activation by binding to factor H via elongation factor thermo unstable (EF-Tu)

Virulence, 2020
Mycoplasmas persist in the host for a long time, suggesting that they possess mechanisms for immune evasion. Factor H is a negative regulator of the complement system, which binds to host cells to avoid unexpected complement activation. In this study, we
Yanfei Yu, Jia Wang, Rui Han, Li Wang, Lei Zhang, Amy Yimin Zhang, Jiuqing Xin, Shaoli Li, Yanhua Zeng, Guoqing Shao, Zhixin Feng, Qiyan Xiong   +11 more
doaj   +1 more source

Long-term follow-up of Mycoplasma hyopneumoniae-specific immunity in vaccinated pigs

Veterinary Research, 2023
Mycoplasma hyopneumoniae is the primary agent of enzootic pneumonia in pigs. To minimize the economic losses caused by this disease, M. hyopneumoniae vaccination is commonly practiced. However, the persistence of M. hyopneumoniae vaccine-induced immunity,
Evelien Biebaut, Lisa Beuckelaere, Filip Boyen, Freddy Haesebrouck, Charles-Oliver Gomez-Duran, Bert Devriendt, Dominiek Maes   +6 more
doaj   +1 more source

Identification and characterization of a Mycoplasma hyopneumoniae adhesin [PDF]

Infection and Immunity, 1995
An adhesin of Mycoplasma hyopneumoniae was identified and characterized in this study. A monoclonal antibody (MAb), F2G5, and its F(ab')2 fragments inhibited the adherence of M. hyopneumoniae to porcine tracheal cilia, the natural targets to which the mycoplasma binds during infection. MAb F2G5 detected multiple bands, but predominantly recognized a 97-
Zhang, Qijing, Young, Theresa, Ross, R. F.   +2 more
openaire   +3 more sources

Oral vaccination of piglets against Mycoplasma hyopneumoniae using silica SBA-15 as an adjuvant effectively reduced consolidation lung lesions at slaughter

Scientific Reports, 2021
Mycoplasma (M.) hyopneumoniae is the main pathogen of porcine enzootic pneumonia (PEP). Its controlling is challenging, and requires alternative strategies. This study aimed to develop an oral vaccine against M.
Marina L. Mechler-Dreibi, Henrique M. S. Almeida, Karina Sonalio, Mariela A. C. Martines, Fernando A. M. Petri, Beatriz B. Zambotti, Marcela M. Ferreira, Gabriel Y. Storino, Tereza S. Martins, Hélio J. Montassier, Osvaldo A. Sant’Anna, Márcia C. A. Fantini, Luís Guilherme de Oliveira   +12 more
doaj   +1 more source

Repetitive Elements in Mycoplasma hyopneumoniae Transcriptional Regulation. [PDF]

PLoS ONE, 2016
Transcriptional regulation, a multiple-step process, is still poorly understood in the important pig pathogen Mycoplasma hyopneumoniae. Basic motifs like promoters and terminators have already been described, but no other cis-regulatory elements have ...
Amanda Malvessi Cattani, Franciele Maboni Siqueira, Rafael Lucas Muniz Guedes, Irene Silveira Schrank   +3 more
doaj   +1 more source

Mycoplasma hyopneumoniae Infection Activates the NOD1 Signaling Pathway to Modulate Inflammation

Frontiers in Cellular and Infection Microbiology, 2022
Mycoplasma hyopneumoniae is a highly contagious pathogen causing porcine enzootic pneumonia, which elicits prolonged inflammatory response modulated by pattern recognition receptors (PRRs).
Wei Liu, Pengcheng Jiang, Pengcheng Jiang, Keli Yang, Qiqi Song, Fangyan Yuan, Zewen Liu, Ting Gao, Danna Zhou, Rui Guo, Chang Li, Pei Sun, Yongxiang Tian   +12 more
doaj   +1 more source