Results 131 to 140 of about 904,551 (309)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Mycoplasma Pneumoniae Infections: An Update

According to the CDC, this educational webinar will provide the latest updates on Mycoplasma respiratory infections, increasing in 2024, especially among younger children.
Kaushik, Ashlesha
core   +1 more source

Intracranial infection in an adult caused by Mycoplasma hominis, diagnosed using mNGS technology: a case report

Frontiers in Medicine
Mycoplasma hominis is a rare cause of adult central nervous system infections, posing significant diagnostic challenges due to its fastidious growth requirements and high false-negative rate in conventional cultures.
Kai-Meng Wang, Na Mu, He-Bo Wang
doaj   +1 more source

Various clinical manifestations of Mycoplasma pneumoniae infections [PDF]

, 2009
Mycoplasma pneumoniae was first isolated over 100 years ago. There are intensive researches on this atypical pathogen causing various diseases at humans, lasting for over 50 years.
Kalicki, Bolesław, Grad, Anna, Jung, Anna, Bartoszewicz, Ludmiła, Żuber, Janusz, Fabisiewicz, Agnieszka   +5 more
core  

Severe Mycoplasma hominis infections in two renal transplant patients

, 2004
Systemic infections due to Mycoplasma hominis are rare and occur mainly in immunocompromised patients. Reported here are the cases of two renal transplant patients with peritonitis who did not respond to empirical antimicrobial treatment.
Jacomo, V., Bescher Ninet, Béatrice Alice, Lew, Daniel Pablo, Rohner, Peter, Schrenzel, Jacques, Garbino, Jorge, Ramla, T., Schnyder, I.   +7 more
core   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Chlamydia trachomatis and mycoplasma infections in tubal pregnancy. [PDF]

Sci Rep, 2019
Liu Y, Zhang Y, Yang D, Xu C, Huang Y, Qing Q, Li D, Liao J, Ding Y, Zhou J, Zhang J, Sun C, Zhou H.   +12 more
europepmc   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Monoklonális antitest Mycoplasma szennyeződésének vizsgálata real-time PCR módszerrel

, 2019
A dolgozat témája a gyógyszeriparban jelenlévő esetleges Mycoplasma szennyeződés kimutatása az alkalmazott sejtvonalakból. A mérés során egy qPCR technológián alapuló gyors kimutatási rendszert alkalmazom, ami a baktérium genomban található konzervált ...
Gáll-Kiss, Beáta
core