Results 231 to 240 of about 77,206 (310)

The Growth Supporting Role of ZDHHC11 Is Linked to the MEF2B–BCL6 Regulatory Circuit in Burkitt Lymphoma

International Journal of Cancer, EarlyView.
MEF2B and BCL6 have established functions in germinal center B‐cell biology and lymphomagenesis. The mechanism of MEF2B deregulation and its significance for cell survival in Burkitt lymphoma however remain unclear. This study highlights MEF2B as a crucial transcription factor in Burkitt lymphoma and suggests ZDHHC11 as an upstream regulator of MEF2B ...
Lotteke J. Y. M. Ziel‐Swier, Karolina Rassek, Yichen Liu, Annika Seitz, Jasper Koerts, Debora de Jong, Bea Rutgers, Anastasiia Kompaniiets, Julia Przybył, Martine E. D. Chamuleau, Anke van den Berg, Agnieszka Dzikiewicz‐Krawczyk, Joost Kluiver   +12 more
wiley   +1 more source

Analysis of risk factors for the development of bronchiolitis obliterans in children with severe <i>Mycoplasma pneumoniae</i> pneumonia. [PDF]

Front Med (Lausanne)
Hou J, Sun R, Ding Z, Jia W, Li P, Fu S, Song C.   +6 more
europepmc   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Concomitant Sexually Transmitted Infections in Patients With Anal Warts: A Single-Center, Cross-Sectional Study in Ho Chi Minh City, Vietnam. [PDF]

Health Sci Rep
Nguyen HT, Doan EVL, Nguyen AP, Bui HM, Huu Le B, Nguyen TTP, Pham NN, Tran TNA.   +7 more
europepmc   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, EarlyView.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Economic burden of <i>Mycoplasma pneumoniae</i> infection in Jinhua City, China: a multicenter cross-sectional study. [PDF]

Front Public Health
Du ZP, Feng YL, Ma X, Ye Z, Li XC, He JJ, Jiang GY, Zhou L, Long ZP, Pang ZF, Zhang GM.   +10 more
europepmc   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

Post-pandemic resurgence and co-detectiondynamics of respiratory pathogens revealed by syndromic multiplex PCR. [PDF]

BMC Microbiol
Aygar IS.
europepmc   +1 more source

Utility of a Combined Diagnostic and Severity Scoring System Based on Complete Blood Count and Derived Immune‐Inflammatory Indicators in Children With Mycoplasma pneumoniae Pneumonia

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a simple, low‐cost scoring system using routine complete blood count (CBC) and derived immune‐inflammatory indicators (LYM%, PLT, PCT, and PLT × LYM) for early diagnosis of Mycoplasma pneumoniae pneumonia (MPP) in 1662 children. Age‐stratified analysis confirmed that key indicators remained significantly higher in the pneumonia ...
Quan Liu, Li Wei, Liang Wang, Xing‐Mei Zhu, Hai‐Feng Wang, Ling Ge   +5 more
wiley   +1 more source

Neutrophil extracellular traps and severe mycoplasma pneumonia: A clinical observational study. [PDF]

Medicine (Baltimore)
Hu Z, Qi L, Yuan L, Zhao B, Jiang J.
europepmc   +1 more source