Results 21 to 30 of about 2,038 (172)
Theoretical perspective on synthetic man‐made life: Learning from the origin of life
Abstract Creating a man‐made life in the laboratory is one of life science’s most intriguing yet challenging problems. Advances in synthetic biology and related theories, particularly those related to the origin of life, have laid the groundwork for further exploration and understanding in this field of artificial life or man‐made life.
Lu Peng +11 more
wiley +1 more source
The convergence of bioinformational and biophysical engineering technologies is accelerating the expansion of the repertoire of biodesign tools, which are moving the barriers beyond the frontiers of yeast research. These novel concepts include the construction of fully synthetic yeast genomes; minimal genomes; supernumerary pan‐genome neochromosomes ...
Thomas A. Dixon +2 more
wiley +1 more source
Leveraging nature to advance data storage: DNA as a storage medium
Schematic overview of DNA data storage.
Kaleb Z. Abram, Zulema Udaondo
wiley +1 more source
Bacteria are rather simple forms of life. However, despite extensive research, many functions of many potentially important proteins have yet to be elucidated even in the model organism Bacillus subtilis. We present a workflow for characterizing unknown genes and proteins, from the initial generation of minimal information to functional identification.
Dennis Wicke +4 more
wiley +1 more source
Immunoelectrophoretic Analysis of Mycoplasma mycoides var. mycoides [PDF]
Acrylamide gel electrophoresis was used to show the similarities and differences in the membrane proteins of two vaccine and two virulent strains of Mycoplasma mycoides var. mycoides. Immunoelectrophoretic (IEP) analysis was also used to partially characterize the associated antigens ...
S S, Stone, S, Razin
openaire +2 more sources
The reference genome of Bacillus subtilis was first sequenced and annotated 25 years ago. At that time, some 42% of the coding sequences could not be assigned a function. In the present annotated update, 15% of the CDS remain functionless. An important contribution of newly identitied functions has been attributed to nucleic acid modifying enzymes and ...
Erhard Bremer +10 more
wiley +1 more source
: The present study aimed to investigate contagious agalactia (CA) in flocks from Pernambuco State. The study involved 225 goats and 63 ewes; 288 milk samples and 100 vaginal swabs were collected in total.
Sandra Batista dos Santos +6 more
doaj +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells. [PDF]
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Gan S, Scarpelli V, Exterkate M.
europepmc +2 more sources
Maternal‐derived antibodies specific to the Ma in goat kids born from vaccinated does were measured from birth to 100 days old. Results showed that 56–70 days of age is the good age to give the first dose of CA vaccine in goat kids. Abstract Background Contagious agalactia (CA) is one of the most important diseases in the small ruminant industry in ...
Mostafa Abdollahi +4 more
wiley +1 more source
Purine metabolism homeostasis is crucial to maintain proper metabolism and bacterial cell physiology. We identified mycobacterial GuaB1 protein as a guanosine 5′‐monophosphate dehydrogenase. GMPR activity is allosterically regulated by the ATP/GTP ratio in a pH‐dependent manner.
Zdeněk Knejzlík +8 more
wiley +1 more source

