Results 21 to 30 of about 2,038 (172)

Theoretical perspective on synthetic man‐made life: Learning from the origin of life

open access: yesQuantitative Biology, Volume 11, Issue 4, Page 376-394, December 2023., 2023
Abstract Creating a man‐made life in the laboratory is one of life science’s most intriguing yet challenging problems. Advances in synthetic biology and related theories, particularly those related to the origin of life, have laid the groundwork for further exploration and understanding in this field of artificial life or man‐made life.
Lu Peng   +11 more
wiley   +1 more source

Visioning synthetic futures for yeast research within the context of current global techno‐political trends

open access: yesYeast, Volume 40, Issue 10, Page 443-456, October 2023., 2023
The convergence of bioinformational and biophysical engineering technologies is accelerating the expansion of the repertoire of biodesign tools, which are moving the barriers beyond the frontiers of yeast research. These novel concepts include the construction of fully synthetic yeast genomes; minimal genomes; supernumerary pan‐genome neochromosomes ...
Thomas A. Dixon   +2 more
wiley   +1 more source

Leveraging nature to advance data storage: DNA as a storage medium

open access: yesMicrobial Biotechnology, Volume 16, Issue 9, Page 1709-1712, September 2023., 2023
Schematic overview of DNA data storage.
Kaleb Z. Abram, Zulema Udaondo
wiley   +1 more source

Understudied proteins and understudied functions in the model bacterium Bacillus subtilis—A major challenge in current research

open access: yesMolecular Microbiology, Volume 120, Issue 1, Page 8-19, July 2023., 2023
Bacteria are rather simple forms of life. However, despite extensive research, many functions of many potentially important proteins have yet to be elucidated even in the model organism Bacillus subtilis. We present a workflow for characterizing unknown genes and proteins, from the initial generation of minimal information to functional identification.
Dennis Wicke   +4 more
wiley   +1 more source

Immunoelectrophoretic Analysis of Mycoplasma mycoides var. mycoides [PDF]

open access: yesInfection and Immunity, 1973
Acrylamide gel electrophoresis was used to show the similarities and differences in the membrane proteins of two vaccine and two virulent strains of Mycoplasma mycoides var. mycoides. Immunoelectrophoretic (IEP) analysis was also used to partially characterize the associated antigens ...
S S, Stone, S, Razin
openaire   +2 more sources

A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century

open access: yesMicrobial Biotechnology, Volume 16, Issue 6, Page 1203-1231, June 2023., 2023
The reference genome of Bacillus subtilis was first sequenced and annotated 25 years ago. At that time, some 42% of the coding sequences could not be assigned a function. In the present annotated update, 15% of the CDS remain functionless. An important contribution of newly identitied functions has been attributed to nucleic acid modifying enzymes and ...
Erhard Bremer   +10 more
wiley   +1 more source

Epidemiology of Mycoplasma agalactiae and Mycoplasma mycoides cluster in flocks of northeastern Brazil

open access: yesCiência Rural, 2018
: The present study aimed to investigate contagious agalactia (CA) in flocks from Pernambuco State. The study involved 225 goats and 63 ewes; 288 milk samples and 100 vaginal swabs were collected in total.
Sandra Batista dos Santos   +6 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells. [PDF]

open access: yesFEBS Lett
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Gan S, Scarpelli V, Exterkate M.
europepmc   +2 more sources

Assessment of the duration of maternal‐derived antibodies specific to the Mycoplasma agalactiae vaccine in goat kids

open access: yesVeterinary Medicine and Science, Volume 8, Issue 5, Page 2119-2125, September 2022., 2022
Maternal‐derived antibodies specific to the Ma in goat kids born from vaccinated does were measured from birth to 100 days old. Results showed that 56–70 days of age is the good age to give the first dose of CA vaccine in goat kids. Abstract Background Contagious agalactia (CA) is one of the most important diseases in the small ruminant industry in ...
Mostafa Abdollahi   +4 more
wiley   +1 more source

The mycobacterial guaB1 gene encodes a guanosine 5′‐monophosphate reductase with a cystathionine‐β‐synthase domain

open access: yesThe FEBS Journal, Volume 289, Issue 18, Page 5571-5598, September 2022., 2022
Purine metabolism homeostasis is crucial to maintain proper metabolism and bacterial cell physiology. We identified mycobacterial GuaB1 protein as a guanosine 5′‐monophosphate dehydrogenase. GMPR activity is allosterically regulated by the ATP/GTP ratio in a pH‐dependent manner.
Zdeněk Knejzlík   +8 more
wiley   +1 more source

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