One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer +4 more
wiley +1 more source
Background Contagious Bovine Pleuropneumonia (CBPP), caused by Mycoplasma mycoides subsp. mycoides, is widespread in sub-Saharan Africa. The current live vaccine T1/44 has limited efficacy and occasionally leads to severe side effects in the animals.
Sacchini Flavio +8 more
doaj +1 more source
The evolving landscape of molecular visualization
Abstract Molecular visualization plays a central role in structural biology, transforming data into representations that reveal how molecular form relates to function. Since the construction of the first protein models in the 1950s, visualization practices have evolved in tandem with experimental and computational advances, shaping both research and ...
Rachel Torrez +3 more
wiley +1 more source
Enzymes of pyrimidine deoxyribonucleotide metabolism in Mycoplasma mycoides subsp. mycoides [PDF]
Cell-free extracts of Mycoplasma mycoides subsp. mycoides were assayed for enzymes associated with the salvage synthesis of pyrimidine deoxyribonucleotides. They possessed kinases for deoxycytidine, (d)CMP, thymidine (deoxyuridine), dTMP, and nucleoside diphosphates; dCTPase and dUTPase; dCMP deaminase; thymidine (deoxyuridine) phosphorylase; and dUMP (
G A, Neale, A, Mitchell, L R, Finch
openaire +2 more sources
Genomic differences between type strain PG1 and field strains of Mycoplasma mycoides subsp. mycoides small-colony type [PDF]
The recently accomplished complete genomic sequence analysis of the type strain PG1 of Mycoplasma mycoides subsp. mycoides small-colony type revealed four large repeated segments of 24, 13, 12, and 8 kb that are flanked by insertion sequence (IS ...
Bischof, Daniela F. +4 more
core +1 more source
Genes found essential in other mycoplasmas are dispensable in Mycoplasma bovis.
Mycoplasmas are regarded to be useful models for studying the minimum genetic complement required for independent survival of an organism. Mycoplasma bovis is a globally distributed pathogen causing pneumonia, mastitis, arthritis, otitis media and ...
Shukriti Sharma +2 more
doaj +1 more source
A Review of Infectious and Non‐Infectious Causes of Pregnancy Loss in Goats
ABSTRACT Goats play a vital role in global agriculture, particularly in developing regions, and are increasingly kept as companion animals. Given their economic and social importance, pregnancy losses in goats represent a substantial challenge, leading to considerable economic losses and raising concerns about animal welfare and public health, as some ...
Friederike Maria Kaus +4 more
wiley +1 more source
Weaving knowledges to support wildlife health surveillance in Kenya's pastoral rangelands
Abstract In wildlife–livestock–human interfaces, pathogens capable of spreading between wild and domestic animals and humans have important implications for conservation outcomes, economics, and public health. Robust wildlife health surveillance can help address these risks.
Brock Bersaglio +4 more
wiley +1 more source
Immunoelectrophoretic Analysis of Mycoplasma mycoides var. mycoides [PDF]
Acrylamide gel electrophoresis was used to show the similarities and differences in the membrane proteins of two vaccine and two virulent strains of Mycoplasma mycoides var. mycoides. Immunoelectrophoretic (IEP) analysis was also used to partially characterize the associated antigens ...
S S, Stone, S, Razin
openaire +2 more sources
A metabolic enzyme as a primary virulence factor of Mycoplasma mycoides subsp. mycoides small colony
During evolution, pathogenic bacteria have developed complex interactions with their hosts. This has frequently involved the acquisition of virulence factors on pathogenicity islands, plasmids, transposons, or prophages, allowing them to colonize ...
Joachim Frey +13 more
core +1 more source

