Results 11 to 20 of about 39,492 (194)
Conjugal Secondary Syphilis With Divergent Cutaneous Manifestations: Papulonodular Variant. [PDF]
Clin Case RepSecondary syphilis (Papulonodular variant). Multiple erythematous papules and nodules on the (a) left side of the neck, (b) posterior neck, and (c) face. (d) Solitary indurated, erythematous papule over the shaft of the penis (arrow). ABSTRACT Syphilis should be considered in patients with atypical papulonodular eruptions, as even conjugal cases may ...
Mathur M +5 more
europepmc +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk +5 more
wiley +1 more source
JPGN Reports, EarlyView.Abstract The diagnosis of autoimmune hepatitis (AIH) is supported by the presence of elevated transaminases, hypergammaglobulinemia, liver biopsy consistent with AIH, and the presence of AIH autoantibodies. In this case presentation, we highlight the challenges associated with diagnosing AIH in a patient with inflammatory bowel disease (IBD) who ...
Benjamin J. Malamet +5 more
wiley +1 more source
Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino +3 more
wiley +1 more source
Drug Hypersensitivity: A Correlation Study From Histopathology to Clinic
JEADV Clinical Practice, EarlyView.ABSTRACT Background Drug hypersensitivity (DH) can present with varied clinical and pathological manifestations that may mislead the referring physician. Available data regarding the concordance between pathological diagnosis and clinical findings in DH are scarce.
Olivier Philip +5 more
wiley +1 more source
Histopathological Aspects of Common Immune Checkpoint Inhibitors Induced Skin Toxicities
JEADV Clinical Practice, EarlyView.ABSTRACT Background The histological characteristics of checkpoint inhibitors‐related adverse events (cirAEs) are not well studied and there are conflicting data regarding their similarities and differences with their idiopathic counterparts. Objectives To investigate the histological characteristics of the most common cirAEs.
Christina Kemanetzi +12 more
wiley +1 more source
Categorization of Reasons for Hospitalizations in Patients With Cutaneous T‐Cell Lymphoma
JEADV Clinical Practice, EarlyView.ABSTRACT Background Cutaneous T‐cell lymphomas (CTCL) can significantly impact patients' quality of life as well as impose a substantial healthcare burden due to their complex management and risk of hospitalization. Objectives This study aimed to identify factors associated with hospital admissions among patients with CTCL and to characterize the ...
Geetha Gowda +6 more
wiley +1 more source
Juvenile Mycosis Fungoides: A Multicenter Retrospective Italian Study
JEADV Clinical Practice, EarlyView.This multicenter retrospective study included 29 juvenile mycosis fungoides (JMF) patients from five Italian centres with confirmed histopathological diagnosis. most often presents with hypopigmented/classic variants and CD8+ phenotype. Early‐onset cases ( < 14 years) show better long‐term outcomes.
Andrea Michelerio +8 more
wiley +1 more source
Pest Management Science, EarlyView.Highly pathogenic isolates of Metarhizium anisopliae attracted Drosophila suzukii. Identifying the responsible compounds for this attraction could help the development of these isolates for pest monitoring and overall pest management. Abstract BACKGROUND Drosophila suzukii, commonly known as spotted wing drosophila (SWD), is a highly invasive and ...
Ibrahim M Farid +7 more
wiley +1 more source
Immunoprofiling Reveals GATA3 as a Prognostic Marker in Transformed Mycosis Fungoides
The Journal of Dermatology, EarlyView.ABSTRACT Transformed mycosis fungoides (TMF) is a rare, aggressive variant of cutaneous T‐cell lymphoma characterized by the presence of large neoplastic cells and poor clinical outcomes. A retrospective cohort of 22 TMF patients was analyzed using immunohistochemistry on formalin‐fixed, paraffin‐embedded (FFPE) tissue for GATA3 (n = 20), T‐bet (n = 22)
Bruno de Castro e Souza +5 more
wiley +1 more source