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Transverse myelitis (TM) includes a pathobiologically heterogeneous syndrome characterized by acute or subacute spinal cord dysfunction resulting in paresis, a sensory level, and autonomic (bladder, bowel, and sexual) impairment below the level of the lesion.
Shin C Beh +2 more
exaly +3 more sources
Severe Immune-Related Neurological Adverse Events Associated With Immune Checkpoint Inhibitor Treatment: A Retrospective Single-Center Study. [PDF]
In a cohort of 2043 patients treated with immune checkpoint inhibitors (ICI), severe neurological immune‐related adverse events (n‐irAEs) occurred in 0.5% of cases. These events predominantly involved the peripheral nervous system (PNS) and showed variable onset.
Grisold A +10 more
europepmc +2 more sources
The diagnosis of myelitis relies on MRI. The purpose of this review is to describe the imaging findings in patients with myelitis through clinical cases. MR findings in Multiple Sclerosis, Neuromyelitis Optica and others Transverse Myelitis are highlighted.
Hodel, J +5 more
openaire +5 more sources
From January to November 2018, there were 90 confirmed cases of acute flaccid myelitis in the United States and 48 suspected cases in Canada.1,2 Injury to the anterior horn cells of the spinal cord causes abrupt-onset limb weakness, pain, paresthesias and areflexia.3 About 25% of patients ...
Gill, P, Bitnun, A, Yeh, E
openaire +2 more sources
Mumps Myelitis—A Rare Cause of Myelitis
ABSTRACT. This report presents a rare case of acute transverse myelitis (ATM) after mumps infection in a 33-year-old male. Symptoms included fever, parotid and scrotal swelling, and subsequent sensory-motor paraparesis. Magnetic resonance imaging revealed long-segment spinal cord hyperintensity, and cerebrospinal fluid analysis showed pleocytosis and ...
Bansal, Kshitij +3 more
openaire +2 more sources
Etanercept-associated myelitis [PDF]
Etanercept is an inhibitor of the pro-inflammatory and immunoregulatory cytokine tumor necrosis factor-α (TNFα). It has been proved highly effective in the treatment of rheumatoid arthritis, psoriasis and ankylosing spondylitis, although several potentially severe side effects have been reported, including infections and allergic reactions.
Finke, Carsten +3 more
openaire +2 more sources
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock +4 more
wiley +1 more source

