Results 171 to 180 of about 67,058 (255)

Glofitamab in Heavily Pretreated Mantle Cell Lymphoma Patients: A Multicenter Real‐World Case Series

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background Relapsed or refractory mantle cell lymphoma (r/r MCL) remains difficult to treat despite therapeutic advances. Methods This multicenter retrospective study included 10 patients with r/r MCL treated with glofitamab across five sites in Austria and Italy before European approval (January 2023–May 2024).
Natalia Rotter, Markus Raderer, Agnes List, Ferdinand Haslbauer, Olga Saini, Alexander Egle, Teresa Magnes, Michael Leisch, Emine Kaynak, Veronika Buxhofer‐Ausch, Beatrice Casadei, Felix Keil, Holger Rumpold, Georg Hess, Richard Greil, Pier Luigi Zinzani, Thomas Melchardt   +16 more
wiley   +1 more source

Critical Role of Molecular-Based Stratification in Low-Risk Myelodysplastic Syndrome with Direct Progression to Acute Myeloid Leukemia: A Case Report. [PDF]

Int J Mol Sci
Mihai SN, Dragu D, Mambet C, Botezatu A, Gurban P, Necula LG, Matei L, Neagu AI, Pitica I, Ataman M, Nedeianu S, Chivu-Economescu M, Bleotu C, Grosu-Ferea CR, Ciufu C, Diaconu CC, Vladareanu AM.   +16 more
europepmc   +1 more source

Association of Frailty With Transfusions, Hospitalizations, and Survival in Patients With Myelodysplastic Syndrome Initiating Hypomethylating Agents

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Prognostic scoring systems in MDS lack functional status measures. We sought to evaluate the influence of frailty on overall survival and care utilization in a national cohort. We conducted a retrospective study in the US Veterans Affairs Healthcare System of patients with MDS initiated on hypomethylating agents (HMAs) from 2004 ...
Anahid Hamparsumian, Jennifer La, Mayuri Dharne, Gary Gilbert, Mary T. Brophy, Nhan V. Do, Dae Hyun Kim, Jane A. Driver, Nathanael R. Fillmore, Clark DuMontier   +9 more
wiley   +1 more source

Concurrent <i>SF3B1</i> Mutation and <i>BCR::ABL1</i> Demonstrating a Myelodysplastic Syndrome Phenotype: A Case Report. [PDF]

EJHaem
Brailovski E, Vahedi A, Lisi V, Dmitrienko S, Mercier FE, Lavallée VP, Assouline S.   +6 more
europepmc   +1 more source

The Predictive Value of Serum Erythropoietin Levels Measured at Diagnosis in Patients With Myelodysplastic Syndromes

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Objectives: To study the predictive and prognostic values of serum erythropoietin levels (sEPO) measured at diagnosis in lower‐risk myelodysplastic syndromes. Methods: We analyzed clinical associations and prognosis with sEPO in 672/1610 patients with at least one year of follow‐up data in the prospective EUMDS study.
Dominic Culligan, Adele Taylor, Alexandra Smith, Catherine Cargo, Howard Oster, Argiris Symeonidis, Reinhard Stauder, Saskia Langemeijer, Luca Malcovati, Pierre Fenaux, Jaroslav Čermák, Eva Hellström‐Lindberg, Juliet Mills, Ioannis Kotsianidis, Maud D'Aveni, Corine van Marrewijk, Marlijn Hoeks, Theo de Witte, David Bowen, Moshe Mittelman   +19 more
wiley   +1 more source

A large dataset of bone marrow cells in myelodysplastic syndrome for classification systems. [PDF]

Sci Data
Shen D, Gao X, Tong J, Feng J, Huang Z, Zhang T, Li J, Zhao S, Zhu Y, Xu Y, Yuan S, Jin C, Tong H.   +12 more
europepmc   +1 more source

N‐Terminal Variant p.Ala2Val in X‐Linked Dyskeratosis Congenita Gene (DKC1) Disrupts Its Post‐Translational Modification and Nucleolar Localization

Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
Major symptoms of dyskeratosis congenita. Predicted nuclear localization site at N‐terminus of DKC1 protein. Comparison of nuclear localization for DKC1 showing normal localization for wild‐type versus disruption of localization for p.Ala2Val. ABSTRACT Background Dyskeratosis congenita (DKC) is typically characterized by the triad of abnormal cutaneous
Taimoor I. Sheikh, John B. Vincent
wiley   +1 more source

Treatment of Relapsed/Refractory t(11;14) Multiple Myeloma and High-Risk Myelodysplastic Syndrome With Venetoclax. [PDF]

Case Rep Hematol
Taylor AO, Clune S, Liu J, Gasparetto C, LeBlanc TW.   +4 more
europepmc   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, Volume 269, Issue 4-5, Page 387-398, August 2026.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Synergistic effects of luspatercept and cyclosporine A in lower-risk myelodysplastic syndrome with red cell aplasia: Two case insights. [PDF]

Leuk Res Rep
Jo T, Sakai T, Noguchi K, Yamaguchi K, Umemoto K, Abe K, Shigematsu K.   +6 more
europepmc   +1 more source