FBXO11 suppression rewires an NPM1-centered interactome influencing the progression of myelodysplastic syndrome. [PDF]
Niederkorn M +28 more
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Marrow Microenvironmental Pathobiology and Therapeutic Opportunities for TP53-Mutated Myelodysplastic Syndrome/Acute Myeloid Leukemia. [PDF]
Hunter CJ, Im AP, Shallis RM.
europepmc +1 more source
骨髄異形成症候群(Myelodysplastic Syndrome, MDS)症例における赤芽球系細胞の形態異常
Takaki Izumi +4 more
openalex +1 more source
Amyloidosis and Myelodysplastic Syndrome
Satoko, Oka +6 more
openaire +2 more sources
A Novel Use of Anifrolumab for a Novel Disease
Objective To explore the potential role of type‐I interferon (IFN‐I) signaling in autoimmune cytopenias outside the context of systemic lupus erythematosus (SLE), and to evaluate the clinical response to off‐label anifrolumab in two patients with fatigue and immune‐mediated cytopenias who did not meet established criteria for SLE.
Zachary Holtz, Adam Schulz, Alexa Meara
wiley +1 more source
Atypical orbital mass as the precursor for myelodysplastic syndrome recurrence: a case report. [PDF]
Demas N, Hernandez J, Timoney P.
europepmc +1 more source
Improved survival after acute graft-versus-host disease diagnosis in the modern era [PDF]
et al.,, Hayashi, Robert J, Vig, Ravi
core +1 more source
DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li +25 more
wiley +1 more source
Severe Hidradenitis Suppurativa and Subsequent Myelodysplastic Syndrome: A Case Report Highlighting Chronic Inflammatory Burden and Carcinogenic Risk. [PDF]
Rosas García MR +4 more
europepmc +1 more source

