Results 271 to 280 of about 123,600 (352)
Mechanochemically Driven Synthesis of Anticancer Cocrystals: A Case Study of Lenalidomide
The combination of crystal engineering and mechanochemical approaches is a powerful strategy for the rational screen and development of new solid forms of active pharmaceutical ingredients (API). New supramolecular patterns formed between an API and a coformer allow the adjustment of physicochemical properties of drugs.
Ana C. S. Carvalho +15 more
wiley +1 more source
Incidence of Second Malignancies Among Children Treated for Cancer With Radiotherapy in Egypt
ABSTRACT Background Survivors of childhood cancer (CCS) are at risk for secondary malignant neoplasms (SMNs): serious late effects of treatment. Radiotherapy (RT) and chemotherapy (CT) are possible causes of SMNs. Aims To measure SMN incidence and characteristics among Egyptian CCS treated with RT, and to compare SMN timing and location based on RT ...
Charlotte L. Sackett +6 more
wiley +1 more source
Minoxidil ameliorates myelodysplastic syndrome by targeting Wnt4 while sparing normal hematopoiesis. [PDF]
Shi X +7 more
europepmc +1 more source
Langerhans Cell Histiocytosis Associated With Chronic Myeloid Leukemia: A Pediatric Case Report
ABSTRACT Background Langerhans cell histiocytosis (LCH) is a rare clonal neoplasm driven by activating mutations in the MAPK pathway, leading to accumulation of pathological Langerhans cells in various tissues. LCH is increasingly associated with secondary malignancies, including leukemias, lymphomas, and solid tumors. However, chronic myeloid leukemia
Atbin Latifi, Sina Yousefian
wiley +1 more source
Prevention and management of febrile neutropenia in acute myeloid leukaemia and higher risk myelodysplastic syndrome: An international survey of current practice. [PDF]
MacPhail A +14 more
europepmc +1 more source
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu +4 more
wiley +1 more source
A Forgotten Foe Returns: The Diagnostic Odyssey of Kala-Azar Masquerading as Myelodysplastic Syndrome in a Post-Elimination Era. [PDF]
Mifty SK +7 more
europepmc +1 more source
Abstract Myelodysplastic syndromes (MDS) are heterogenous disorders in which response assessment remains challenging. In acute myeloid leukemia (AML), measurable residual disease (MRD) by multiparametric flow cytometry (MFC) is prognostic and guides decision‐making after two cycles of intensive chemotherapy, but its role in high‐risk MDS (hrMDS) is ...
Coen R. Veenstra +26 more
wiley +1 more source

