Results 271 to 280 of about 123,600 (352)

Mechanochemically Driven Synthesis of Anticancer Cocrystals: A Case Study of Lenalidomide

open access: yesChemistry–Methods, Volume 6, Issue 5, May 2026.
The combination of crystal engineering and mechanochemical approaches is a powerful strategy for the rational screen and development of new solid forms of active pharmaceutical ingredients (API). New supramolecular patterns formed between an API and a coformer allow the adjustment of physicochemical properties of drugs.
Ana C. S. Carvalho   +15 more
wiley   +1 more source

Incidence of Second Malignancies Among Children Treated for Cancer With Radiotherapy in Egypt

open access: yesCancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Survivors of childhood cancer (CCS) are at risk for secondary malignant neoplasms (SMNs): serious late effects of treatment. Radiotherapy (RT) and chemotherapy (CT) are possible causes of SMNs. Aims To measure SMN incidence and characteristics among Egyptian CCS treated with RT, and to compare SMN timing and location based on RT ...
Charlotte L. Sackett   +6 more
wiley   +1 more source

Minoxidil ameliorates myelodysplastic syndrome by targeting Wnt4 while sparing normal hematopoiesis. [PDF]

open access: yesCell Commun Signal
Shi X   +7 more
europepmc   +1 more source

Langerhans Cell Histiocytosis Associated With Chronic Myeloid Leukemia: A Pediatric Case Report

open access: yesCancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Langerhans cell histiocytosis (LCH) is a rare clonal neoplasm driven by activating mutations in the MAPK pathway, leading to accumulation of pathological Langerhans cells in various tissues. LCH is increasingly associated with secondary malignancies, including leukemias, lymphomas, and solid tumors. However, chronic myeloid leukemia
Atbin Latifi, Sina Yousefian
wiley   +1 more source

Prevention and management of febrile neutropenia in acute myeloid leukaemia and higher risk myelodysplastic syndrome: An international survey of current practice. [PDF]

open access: yesBr J Haematol
MacPhail A   +14 more
europepmc   +1 more source

Targeting the nuclear export receptor exportin‐1 in acute myeloid leukaemia: From biology to clinical translation

open access: yesClinical and Translational Medicine, Volume 16, Issue 5, May 2026.
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu   +4 more
wiley   +1 more source

Prognostic value of measurable residual disease in high‐risk MDS after intensive chemotherapy in HOVON‐SAKK studies

open access: yesHemaSphere, Volume 10, Issue 5, May 2026.
Abstract Myelodysplastic syndromes (MDS) are heterogenous disorders in which response assessment remains challenging. In acute myeloid leukemia (AML), measurable residual disease (MRD) by multiparametric flow cytometry (MFC) is prognostic and guides decision‐making after two cycles of intensive chemotherapy, but its role in high‐risk MDS (hrMDS) is ...
Coen R. Veenstra   +26 more
wiley   +1 more source

Anti-IH in myelodysplastic syndrome. [PDF]

open access: yesPract Lab Med
Wongba K   +3 more
europepmc   +1 more source

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