Results 101 to 110 of about 33,638 (296)
JAK-2 inhibitors and allogeneic transplant in myelofibrosis [PDF]
, 2015 7The activation of the JAK1/JAK2 pathway plays a crucial role in the pathogenesis of myelofibrosis. Treatment with the JAK2 inhibitor ruxolitinib demonstrated to reduce splenomegaly and symptoms in patients affected by myelofibrosis, leading to a ...
Cigana, C +6 more
core
Are we ignoring sex differences in haematological malignancies? A call for improved reporting
British Journal of Haematology, EarlyView.A large body of data indicates that there are sex differences in the incidence of haematological malignancies, their clinical presentation and molecular profiles, and possibly also their aetiologies. Furthermore, sex‐related differences exist in treatment tolerability and outcomes.
Ora Paltiel +2 more
wiley +1 more source
Proceedings of the Royal Society of Medicine, 1952 R B, FRANKS, J S, RICHARDSON
openaire +2 more sources
The degree of anisocytosis predicts survival in patients with primary myelofibrosis [PDF]
, 2016 Introduction: Red cell distribution width (RDW) provides a quantitative measure of anisocytosis and it is associated with the presence of subclinical systemic inflammation and a poor outcome in a variety of diseases when elevated.
Hariš, Višnja +10 more
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Non-driver mutations in myeloproliferative neoplasm-associated myelofibrosis
Journal of Hematology & Oncology, 2017 We studied non-driver mutations in 62 subjects with myeloproliferative neoplasm (MPN)-associated myelofibrosis upon diagnosis, including 45 subjects with primary myelofibrosis (PMF) and 17 with post-polycythemia vera or post-essential thrombocythemia ...
Bing Li +11 more
doaj +1 more source
Ruxolitinib in the treatment of polycythemia vera: patient selection and special considerations. [PDF]
, 2016 The discovery of JAK2 V617F mutation in the mid-2000s started to fill the gap between clinical presentation of polycythemia vera (PV), first described by Vaquez at the end of the 19th century, and spontaneous erythroid colony formation, reported by ...
Alberio, L., Blum, S., Martins, F.
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Cytopathology, EarlyView.The WHO System is an international effort to standardise category definitions, establish the key diagnostic cytopathological features of entities of the lung, propose the best use of ancillary tests in lung specimens, encourage the use of standardised pathology reports containing essential components in an integrated report and propose estimates of the
Zahra Maleki, Sule Canberk, Andrew Field
wiley +1 more source
Extramedullary myeloid tumors in primary myelofibrosis [PDF]
, 1965 Philip Lieberman +2 more
openalex +1 more source
Developmental Medicine &Child Neurology, EarlyView.Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B.
Russell C. Dale +14 more
wiley +1 more source
Use of Testosterone and Busulfan in the Treatment of Myelofibrosis with Myeloid Metaplasia [PDF]
, 1964 Richard T. Silver +3 more
openalex +1 more source