Results 161 to 170 of about 33,638 (296)

Idiopathic Myelofibrosis (Agnogenic Myeloid Metaplasia) in a Marmoset (Callithrix jacchus): Hematologic and Histopathologic Changes [PDF]

, 1997
Kanwar Nasir M. Khan, Ann Logan, Erik Blomquist   +2 more
openalex   +1 more source

VPS45 Contributes to the Progression of Hepatocellular Carcinoma by Triggering the Wnt/β‐Catenin Signaling Pathway

Molecular Carcinogenesis, Volume 64, Issue 4, Page 744-755, April 2025.
ABSTRACT Vacuolar protein sorting 45 (VPS45) has recently been implicated in the development of ovarian cancer and non‐small cell lung cancer. However, its role in the onset and progression of hepatocellular carcinoma (HCC) remains unclear. This study aims to elucidate the function of VPS45 in HCC.
Renhou Zhi, Qi Li, Huiqin Zhang, Fan Fan
wiley   +1 more source

Adaptive dosing of high‐dose busulfan in real‐world adult patients undergoing haematopoietic cell transplant conditioning

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1171-1181, April 2025.
Aim To evaluate the effectiveness of a Bayesian adaptive dosing strategy in achieving target busulfan exposure in adult patients undergoing haematopoietic cell transplantation (HCT). Methods This study included 71 adult patients scheduled to receive high‐dose busulfan. Busulfan was administered to achieve a cumulative area under the curve (AUC) of 66.0 
Dorian Protzenko, Benjamin Bouchacourt, Laure Carriat, Paul Maroselli, Clara Boéri, Raynier Devillier, Joseph Ciccolini   +6 more
wiley   +1 more source

Acute Myelofibrosis

, 1984
Luan D. Truong, Abdus Saleem, Mary R. Schwartz   +2 more
openalex   +1 more source

Olutasidenib demonstrates significant clinical activity in mutated IDH1 acute myeloid leukaemia arising from a prior myeloproliferative neoplasm

British Journal of Haematology, Volume 206, Issue 4, Page 1121-1128, April 2025.
Outcomes with olutasidenib appear appreciably better than previous reports of other therapies for blast‐phase myeloproliferative neoplasm (MPN), supporting the role for olutasidenib‐based therapy in mIDH1 AML secondary to MPN. Summary Acute myeloid leukaemia (AML) arising from a myeloproliferative neoplasm (MPN) is more aggressive and less responsive ...
Stéphane De Botton, Christian Récher, Jorge Cortes, Antonio Curti, Pierre Fenaux, Pierre Peterlin, Arnaud Pigneux, Karen Yee, Andrew Wei, Alice Mims, Gary Schiller, Mwe Mwe Chao, Hua Tian, Justin M. Watts   +13 more
wiley   +1 more source

Pulmonary hypertension in patients with myelofibrosis secondary to myeloproliferative diseases [PDF]

, 1999
Guillermo Garc�a-Manero, Stephen J. Schuster, Herbert Patrick, J. J. Martinez   +3 more
openalex   +1 more source

Advancing the outcomes of AML out of antecedent MPN by targeting mutated IDH1

British Journal of Haematology, Volume 206, Issue 4, Page 1250-1252, April 2025.
Outcomes of myeloproliferative neoplasms (MPN)‐associated acute leukaemias are dismal with conventional therapy. Approximately 20% of MPN‐associated acute leukaemias have mutations in isocitrate dehydrogenase (IDH). Olutasidenib, and inhibitor of IDH1, demonstrates important clinical benefits in MPN‐associated leukaemia with IDH1 mutation.
Keith W. Pratz
wiley   +1 more source

Increased proliferation of bone marrow-derived fibroblasts in primitive hypertrophic osteoarthropathy with severe myelofibrosis [PDF]

, 1995
Michaëla Fontenay, Évelyne Dupuy, Eliane Berrou, G Tobelem, Marijke Bryckaert   +4 more
openalex   +1 more source

Prevalence of cytopenia(s) and somatic variants in patients with DDX41 mutant germline predisposition syndrome

British Journal of Haematology, Volume 206, Issue 4, Page 1109-1120, April 2025.
Summary Germline variants in DDX41 (DDX41MT‐germline predisposition syndrome [GPS]) are associated with predisposition to haematological malignancies (HM), including lymphoid and myeloid neoplasms (MN). We retrospectively analysed the clinical and molecular features of 195 patients diagnosed and treated at Mayo Clinic with DDX41MT‐GPS.
Yael Kusne, Talha Badar, Terra Lasho, Ludovica Marando, Abhishek A. Mangaonkar, Christy Finke, James M. Foran, Aref Al‐Kali, Jeanne Palmer, Cecilia Arana Yi, Hassan B. Alkhateeb, Naseema Gangat, David Viswanatha, Mark R. Litzow, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik   +16 more
wiley   +1 more source

Thrombopoietin‐responsive essential thrombocythaemia with myelofibrosis [PDF]

, 1997
Shuji Ozaki, Masaaki Kosaka, Keiji Ozaki, Shingo Wakatsuki, Toshihiro Hashimoto, Hiroshi Miyazaki   +5 more
openalex   +1 more source