Results 271 to 280 of about 33,638 (296)

Chromosome Abnormalities in Myelofibrosis [PDF]

open access: possibleActa Haematologica, 1987
Cytogenetic analysis was performed on megakaryocyte-enriched cell fractions obtained by separation on discontinuous Percoll gradients from blood, bone marrow, and ascitic fluid of 12 patients with myelofibrosis with myeloid metaplasia (MMM). The most common abnormalities appeared to involve chromosomes 1, 3, 7, 8, 11, 13, 21 and 22.
Paolo Tomasi   +3 more
openaire   +2 more sources

Differential diagnosis of myelofibrosis based on WHO 2008 criteria: Acute panmyelosis with myelofibrosis, acute megakaryoblastic leukemia with myelofibrosis, primary myelofibrosis and myelodysplastic syndrome with myelofibrosis

International Journal of Laboratory Hematology, 2013
SummaryIntroductionThe aim of this study was to characterize clinicopathological features of acute panmyelosis with myelofibrosis (APMF), acute megakaryoblastic leukemia with myelofibrosis (AMKL‐MF), primary myelofibrosis (PMF) and myelodysplastic syndrome with myelofibrosis (MDS‐MF) in order to provide the keys to the differential diagnosis of bone ...
E, Bae   +10 more
openaire   +3 more sources

Myelofibrosis Secondary to Hyperparathyroidism [PDF]

open access: possibleExperimental and Clinical Endocrinology & Diabetes, 2004
We report on a young female who had presented with fatigue, bilateral knee pain and gait disturbance. Primary hyperparathyroidism was diagnosed together with splenomegaly and anemia. Bone marrow biopsy revealed myelofibrosis. A parathyroid adenoma was excised during surgical intervention.
Rumeyza Kazancioglu   +5 more
openaire   +2 more sources

Romiplostim-induced myelofibrosis

Blood, 2013
![Figure][1] A 55-year-old woman with chronic refractory idiopathic thrombocytopenic purpura (ITP) presented with gum bleeding for 1 day. Over the course of several years, she had failed, or became resistant to, multiple treatments including glucocorticoids, intravenous immunoglobulin,
Michele R. Roullet, Armin Rashidi
openaire   +3 more sources

Acute Myelofibrosis

American Journal of Clinical Pathology, 1982
This report describes a 20-year-old patient with rapidly fatal fibrosis of the bone marrow associated with leukopenia, anemia, and large number of myeloblasts in peripheral blood. The bone marrow revealed extensive fibrosis and hyperplasia of the myeloblasts and megakaryocytes.
openaire   +2 more sources

Pyoderma gangrenosum with myelofibrosis

The American Journal of Medicine, 1987
Pyoderma gangrenosum is a papulovesicular skin disorder commonly associated with underlying systemic disease, but rarely with the myeloproliferative syndromes. A case of rapidly progressive pyoderma is cited in a 77-year-old white man who had no other evidence of disease aside from macrocytic anemia.
Frank J. Kroboth   +2 more
openaire   +3 more sources

The ABCCs of myelofibrosis [PDF]

open access: possibleBlood, 2005
Comment on Barosi et al, page [2849][1] “The illness which he'd been smitten should have been analyzed when caught something like spleen that scourge of Britain or Russia's chondria for short” —Alexander Pushkin Eugene Onegin (1823), stanza 38 For nearly 150 years, the ...
openaire   +1 more source

Therapeutic approaches in myelofibrosis

Expert Opinion on Pharmacotherapy, 2011
Myeloproliferative neoplasm (MPN)-associated myelofibrosis is the most disabling of the classical Philadelphia-negative MPNs. The discovery that a gain-of-function mutation of JAK2 (JAK2V617F) is present in more than 60% of patients with MPN-associated myelofibrosis has provided a new target for innovative treatment strategies.This review discusses the
G. Barosi   +2 more
openaire   +4 more sources

Myelofibrosis in Young Adults

Acta Haematologica, 1983
3 young adults with myelofibrosis, a rare disease in this age-group, are presented. Their clinical course was distinguished by a virtually asymptomatic state at time of diagnosis and a stable, or very slowly progressive course over a 4- to 5-year follow-up.
Oded Shalev   +3 more
openaire   +3 more sources

Primary myelofibrosis

2010
Myelofibrosis is a reactive process common to many malignant and benign disorders. Primary myelofibrosis is a chronic myeloproliferative disorder of unknown aetiology that involves a multipotent haemopoietic progenitor cell and results in abnormalities in red cell, white cell, and platelet production in association with marrow fibrosis and ...
openaire   +1 more source

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