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Acute Panmyelosis with Myelofibrosis
Leukemia & Lymphoma, 2004Acute panmyelosis with myelofibrosis (APMF) is an ill-defined disorder that may either evolve as a clonal hematopoietic condition or as a sequel of toxic exposure to the bone marrow (BM). Therefore, controversy and discussion continues as to whether APMF may be considered as a hyperfibrotic (de novo) myelodysplastic syndrome (MDS), as acute myeloid ...
Thiele, Juergen +2 more
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Myelofibrosis with myeloid metaplasia
Hematology/Oncology Clinics of North America, 2003MMM is a chronic myeloproliferative disorder characterized by bone marrow fibrosis and neoangiogenesis, constitutive release ofa high number of CD34+ stem cells from the bone marrow, and extramedullary hematopoiesis. It presents with heterogeneous clinical features in which anemia and progression to symptomatic splenomegaly dominate.
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2018
The main objectives of this chapter are to review the wide array of toxicologic insults that may result in bone marrow damage and subsequent development of bone marrow fibrosis (myelofibrosis) in humans and animals. Etiologic and morphologic features of primary myelofibrosis (a clonally derived myeloproliferative neoplastic disease) are compared to ...
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The main objectives of this chapter are to review the wide array of toxicologic insults that may result in bone marrow damage and subsequent development of bone marrow fibrosis (myelofibrosis) in humans and animals. Etiologic and morphologic features of primary myelofibrosis (a clonally derived myeloproliferative neoplastic disease) are compared to ...
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Myelofibrosis: pathogenesis of myelofibrosis with myeloid metaplasia
Springer Seminars in Immunopathology, 2000Marie-Claire Martyré +1 more
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