Results 11 to 20 of about 49,882 (187)
Myelogenous Leukemia in the Rat [PDF]
Abstract Observations on growth and other characteristics of subcutaneously transplanted chloroleukemia in non-inbred rats have been described in this report. This chloroleukemia cytologically is an acute or subacute, not chronic, myelogenous leukemia.
W C, MOLONEY +3 more
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Chronic Myelogenous Leukemia [PDF]
Chronic myelogenous leukemia (CML) is the one of the most common chronic myeloproliferative disorders. It has become the paradigmatic disease for molecular diagnosis and monitoring for several reasons: (1) CML has a unitary molecular definition, requiring the demonstration of the t(9;22)(q34;q11) chromosomal translocation or its product, the BCR-ABL ...
Susan, O'Brien +19 more
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ACUTE MYELOGENIC LEUKÆMIA [PDF]
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Billings, Frank, Capps, Joseph A.
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CHRONIC MYELOGENOUS LEUKAEMIA [PDF]
In the last decade, improvements in both non-transplant and transplant therapy have extended the lives of patients with CML, particularly those in chronic phase. The future will probably bring a greater understanding of molecular leukaemogenesis and options for treating CML. Non-transplant therapies in development include novel agents and
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Bulbine natalensis and Chorophytum comosum are potential medicinal source for the treatment of cancers. Chronic myeloid leukaemia is a hematopoietic stem cells disorder treated by tyrosine kinase inhibitors but often cause recurrence of the leukaemia ...
B. Padayachee, F. Odun-Ayo, L. Reddy
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Chronic myeloid leukemia: past, present, future [PDF]
The discovery of the Philadelphia chromosome in 1960, and of theBCR-ABL oncogene in 1984, enabled the development in subsequentyears of a targeted therapy that revolutionized the treatment of chronic myeloid leukemia, thus changing its natural history ...
Patricia Weinschenker Bollmann +1 more
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The prognosis of older patients with acute myelogenous leukemia is generally poor. The interleukin-3 receptor α-chain (CD123) is highly expressed on the surface of acute leukemia cells compared with normal hematopoietic stem cells.
Erwin M. Lee +12 more
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Acute liver failure is a rare but catastrophic syndrome. Liver function tests usually reveal cholestatic or hepatocellular pattern, but in this case, we report a previously undescribed manifestation of this condition as isolated hyperbilirubinemia.
Nasrin Gholami +4 more
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Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia.
Pradyumna Agasthi +4 more
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Although farnesyltransferase inhibitors have shown promising activity in relapsed lymphoma and sporadic activity in acute myelogenous leukemia, their mechanism of cytotoxicity is incompletely understood, making development of predictive biomarkers ...
Husheng Ding +14 more
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