Results 11 to 20 of about 49,882 (187)

Myelogenous Leukemia in the Rat [PDF]

open access: yesBlood, 1962
Abstract Observations on growth and other characteristics of subcutaneously transplanted chloroleukemia in non-inbred rats have been described in this report. This chloroleukemia cytologically is an acute or subacute, not chronic, myelogenous leukemia.
W C, MOLONEY   +3 more
openaire   +2 more sources

Chronic Myelogenous Leukemia [PDF]

open access: yesJournal of the National Comprehensive Cancer Network, 2012
Chronic myelogenous leukemia (CML) is the one of the most common chronic myeloproliferative disorders. It has become the paradigmatic disease for molecular diagnosis and monitoring for several reasons: (1) CML has a unitary molecular definition, requiring the demonstration of the t(9;22)(q34;q11) chromosomal translocation or its product, the BCR-ABL ...
Susan, O'Brien   +19 more
openaire   +2 more sources

ACUTE MYELOGENIC LEUKÆMIA [PDF]

open access: yesThe American Journal of the Medical Sciences, 1903
n ...
Billings, Frank, Capps, Joseph A.
openaire   +2 more sources

CHRONIC MYELOGENOUS LEUKAEMIA [PDF]

open access: yesBritish Journal of Haematology, 2000
In the last decade, improvements in both non-transplant and transplant therapy have extended the lives of patients with CML, particularly those in chronic phase. The future will probably bring a greater understanding of molecular leukaemogenesis and options for treating CML. Non-transplant therapies in development include novel agents and
openaire   +2 more sources

Apoptotic effect of Bulbine Natalensis and Chlorophytum Comosum in myelogenous Leukemia K562 cell line

open access: yesBrazilian Journal of Biology, 2021
Bulbine natalensis and Chorophytum comosum are potential medicinal source for the treatment of cancers. Chronic myeloid leukaemia is a hematopoietic stem cells disorder treated by tyrosine kinase inhibitors but often cause recurrence of the leukaemia ...
B. Padayachee, F. Odun-Ayo, L. Reddy
doaj   +1 more source

Chronic myeloid leukemia: past, present, future [PDF]

open access: yesEinstein (São Paulo), 2011
The discovery of the Philadelphia chromosome in 1960, and of theBCR-ABL oncogene in 1984, enabled the development in subsequentyears of a targeted therapy that revolutionized the treatment of chronic myeloid leukemia, thus changing its natural history ...
Patricia Weinschenker Bollmann   +1 more
doaj  

Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice

open access: yesHaematologica, 2015
The prognosis of older patients with acute myelogenous leukemia is generally poor. The interleukin-3 receptor α-chain (CD123) is highly expressed on the surface of acute leukemia cells compared with normal hematopoietic stem cells.
Erwin M. Lee   +12 more
doaj   +1 more source

Isolated hyperbilirubinemia as the manifestation of acute liver failure in a patient with acute myelogenous leukemia and COVID-19 infection

open access: yesEuropean Journal of Translational Myology, 2021
Acute liver failure is a rare but catastrophic syndrome. Liver function tests usually reveal cholestatic or hepatocellular pattern, but in this case, we report a previously undescribed manifestation of this condition as isolated hyperbilirubinemia.
Nasrin Gholami   +4 more
doaj   +1 more source

Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy

open access: yesCase Reports in Cardiology, 2018
Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia.
Pradyumna Agasthi   +4 more
doaj   +1 more source

Farnesyltransferase inhibitor tipifarnib inhibits Rheb prenylation and stabilizes Bax in acute myelogenous leukemia cells

open access: yesHaematologica, 2014
Although farnesyltransferase inhibitors have shown promising activity in relapsed lymphoma and sporadic activity in acute myelogenous leukemia, their mechanism of cytotoxicity is incompletely understood, making development of predictive biomarkers ...
Husheng Ding   +14 more
doaj   +1 more source

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