Results 71 to 80 of about 128,118 (293)

A case of chronic myelogenous leukemia with the T315I mutation who progressed to myeloid blast phase and was successfully treated with asciminib

Clinical Case Reports, 2022
Patients with chronic myelogenous leukemia (CML) harboring the T315I mutation who progress to blast phase CML while on ponatinib may be successfully treated with asciminib monotherapy following induction therapy with cytotoxic chemotherapy.
Sarah Tomassetti, Jennifer Lee, Xin Qing
doaj   +1 more source

Concomitant JAK2 V617F-positive polycythemia vera and BCR-ABL-positive chronic myelogenous leukemia treated with ruxolitinib and dasatinib

Blood Cancer Journal, 2015
Concomitant JAK2 V617F-positive polycythemia vera and BCR-ABL -positive chronic myelogenous leukemia treated with ruxolitinib and ...
A. Zhou, E. Knoche, E. Engle, Daniel A. C. Fisher, S. Oh   +4 more
semanticscholar   +1 more source

Prediction of neutrophil nadir and recovery following paediatric haematopoietic cell transplantation with busulfan conditioning

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 568-578, February 2026.
Aims In haematopoietic cell transplantation (HCT), neutropenia resulting from myelosuppression is an expected endpoint following busulfan‐based conditioning. However, if prolonged, neutropenia can lead to complications like serious infection and death.
Beth Apsel Winger, Joseph W. Polli, Janel Long‐Boyle, Andrew Weber, Jordan Brooks, Jaimit Parikh, Valeriu Damian   +6 more
wiley   +1 more source

Mechanism Underlying the Reversal of Drug Resistance in P-Glycoprotein-Expressing Leukemia Cells by Pinoresinol and the Study of a Derivative [PDF]

, 2017
P-glycoprotein (P-gp) is a membrane protein associated with multidrug resistance (MDR) due to its key role in mediating the traffic of chemotherapeutic drugs outside cancer cells, leading to a cellular response that hinders efforts toward successful ...
Carpinella, Maria Cecilia, Gancedo, Samanta, González, María Laura, Joray, Mariana Belén, Laiolo, Jerónimo, Lanza Castronuovo, Priscila Ailin, Maccioni, Mariana, Molina, Gabriela, Palacios, Sara Maria, Rumjanek, Vivian, Vera, Domingo Mariano Adolfo   +10 more
core   +2 more sources

Trends in US Hematology/Oncology Physician Perceptions and Referral Practices for Hematopoietic Cell Transplant: A National Survey Conducted by NMDP

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background To evaluate trends in allogeneic hematopoietic cell transplant (HCT) referral perceptions and practices, we compared surveys of Hematology‐Oncology (Hem‐Onc) physicians conducted in 2015 (N = 150), 2019 (N = 302), and 2024 (N = 183) and reported changes over time.
Aye Mon Thida, Ankita Shah, Kelley Frederick (Steffens), Samantha Watters, Mingqian Duan, Steven Devine, Susan T. Vadaparampil, Joseph Pidala   +7 more
wiley   +1 more source

Biomarkers of leukemia risk: benzene as a model. [PDF]

, 1998
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core   +3 more sources

Total Synthesis of the Cyanobacterial Alkaloid Nostodione A

European Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.
The total synthesis of the alkaloid nostodione A is successfully achieved utilizing 3,4‐dihydrocyclopenta[b]indole‐1,2‐dione as a key intermediate. The sensitive benzylidene moiety is introduced via a Knoevenagel condensation with p‐hydroxybenzaldehyde.
Oscar F. Casadiego‐Díaz, Ángel Rentería‐Gómez, Teresa Ramírez‐Apan, Rubén O. Torres‐Ochoa   +3 more
wiley   +1 more source

Polypharmacy and potentially inappropriate medication use in geriatric oncology. [PDF]

, 2016
Polypharmacy is a highly prevalent problem in older persons, and is challenging to assess and improve due to variations in definitions of the problem and the heterogeneous methods of medication review and reduction.
Aparicio, Appleton, Badgwell, Balducci, Budnitz, Bushardt, Caillet, Currow, de Glas, Dimitrow, Elliot, Fede, Freyer, Fried, Gajra, Gillette, Gnjidic, Gu, Guaraldo, Guthrie, Gómez, Hajjar, Hamaker, Hanigan, Hanlon, Hilmer, Horgan, Hovstadius, Huiart, Hurria, Institute of Medicine (U.S.). Committee on Identifying Priority Areas for Quality Improvement, Iyer, Jolly, Kalsi, Kanesvaran, Kantor, Kierner, Kim, Klepin, Kohn, Kohn, Korc-Grodzicki, Kouladjian, Lees, Maggiore, Maggiore, Nightingale, O'Mahony, Palumbo, Panel, Parks, Patterson, Payne, Prithviraj, Riechelmann, Saarelainen, Samsa, Scott, Sehgal, Shah, Todd, Todd, Turner, Turner, Woopen, Şenel   +65 more
core   +2 more sources

Transcriptome sequencing of hematopoietic stem cells and chronic myelgenous leukemia stem cells

Genomics Data, 2016
Dipeptide species are accumulated in the chronic myelogenous leukemia (CML) stem cells [1]. To investigate the molecular mechanisms of the accumulation of dipeptide species in CML stem cells, we performed transcriptome sequencing of long-term stem cells,
Junil Kim, Seong-Jin Kim, Kazuhito Naka
doaj   +1 more source

Frailty in Patients With Hematologic Malignancies and Patients Undergoing Hematopoietic Stem Cell Transplantation: A Systematic Review

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) is associated with significant morbidity and mortality. Frailty further increases these risks in recipients of HSCT. This systematic review analyzes the extent of frailty in patients with hematologic malignancies and patients undergoing HSCT, and explores the associations between ...
Marit Bakken, Marie Roko Kallager, Marie Hamilton Larsen, Simen A. Steindal, Kristin J. Skaarud   +4 more
wiley   +1 more source