Results 91 to 100 of about 477,278 (318)
Studies of Diseases of the Lymphoid and Myeloid Tissues [PDF]
, 1932 Frederic Parker +3 more
openalex +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
FEBS Open Bio, EarlyView.PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
Radioactive phosphorus. II. In the treatment of myeloid leukemia [PDF]
, 1951 Henry D. Diamond, Lloyd F. Craver
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone +19 more
wiley +1 more source
An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation
Frontiers in Microbiology, 2019 Herpesviruses undergo life-long latent infection which can be life-threatening in the immunocompromised. Models of latency and reactivation of human cytomegalovirus (HCMV) include primary myeloid cells, cells known to be important for HCMV latent ...
Emma Poole +20 more
doaj +1 more source
Acute Leukaemia and So-Called Mediastinal 'Leukosarcomatosis' (Sternberg): With the Account of a Case Accompanied by Myeloid Substitution of the Hilus-Fat of the Kidneys [PDF]
, 1919 F. P. Weber
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang +11 more
wiley +1 more source
Medullary Aplasia in Chronic Myeloid Leukaemia during Busulphan Therapy [PDF]
, 1957 F. G. J. Hayhoe, David L. Kok
openalex +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source