Results 151 to 160 of about 586,559 (303)

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao   +11 more
wiley   +1 more source

Evaluating survival after allogeneic bone marrow transplant for chronic myeloid leukaemia in chronic phase: a comparison of transplant versus no transplant in cohort of 258 patients first seen in Italy between 1984 and 1986.

open access: yes, 1993
Information on the outcome of allogeneic bone marrow transplant (BMT) for chronic myeloid leukaemia (CML) was previously provided by BMT centres or registries.
The Italian Cooperative Study Group on Chronic Myeloid Leukemia   +1 more
core  

Chromothripsis in myeloid malignancies

open access: yesAnnals of Hematology
AbstractChromothripsis refers to massive genomic rearrangements developed during a catastrophic event. In total acute myeloid leukemia (AML), the incidence of chromothripsis ranges from 0 to 6.6%, in cases of complex karyotype AML, the incidence of chromothripsis ranges from 27.3 to 100%, whereas in cases of AML with TP53 mutations, the incidence ...
openaire   +2 more sources

Immune remodeling and myeloid signature in the bone marrow niche of MYCN-driven neuroblastoma. [PDF]

open access: yesBJC Rep
Embaie BT   +6 more
europepmc   +1 more source

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng   +8 more
wiley   +1 more source

Myeloid-derived cells in the eye – distribution, turnover and functional correlates

open access: yes, 2013
Myeloid-derived cells in the eye – distribution, turnover and functional ...
J Kezic (13720393)   +2 more
core  

Outcomes of adult patients with Li-Fraumeni syndrome and myeloid neoplasms. [PDF]

open access: yesCancer
Senapati J   +19 more
europepmc   +1 more source

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