Results 181 to 190 of about 919,731 (432)

Acute Leukaemia and So-Called Mediastinal 'Leukosarcomatosis' (Sternberg): With the Account of a Case Accompanied by Myeloid Substitution of the Hilus-Fat of the Kidneys [PDF]

, 1919
F. P. Weber
openalex   +1 more source

The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism [PDF]

, 2019
Recent evidence suggests that PPARγ agonists may promote anti-tumor immunity. We show that immunogenic PDV cutaneous squamous cell carcinoma (CSCC) tumors are rejected when injected intradermally at a low cell number (1 × 106) into immune competent ...
Derr-Yellin, Ethel, Ermatov, Nurmukambed, Konger, Raymond L., Ren, Lu, Sahu, Ravi P.   +4 more
core   +1 more source

Breast myeloid sarcoma [PDF]

eJHaem, 2021
Adam C. Gonzalez, Felix A. Olobatuyi, Kirill A. Lyapichev   +2 more
openaire   +4 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

A mathematical model of clonal hematopoiesis explaining phase transitions in myeloid leukemia [PDF]

arXiv
This study presents a mathematical model describing cloned hematopoiesis in chronic myeloid leukemia (CML) through a nonlinear system of differential equations. The primary objective is to understand the progression from normal hematopoiesis to the chronic and accelerated-acute phases in myeloid leukemia.
arxiv  

Aleukaemic Myeloid Leukaemia Presenting as Aplastic Anaemia [PDF]

, 1951
Andrew Black, M. J. Meynell
openalex   +1 more source

Acute myeloid leukaemia

Hematology, 2014
Acute myeloid leukaemia (AML) is a type of cancer of the part of the bone marrow that normally makes ‘myeloid’ cells.
Matthew Smith, Sandra Hassan
openaire   +3 more sources

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Long‐Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia

New England Journal of Medicine, 2017
Background Imatinib, a selective BCR‐ABL1 kinase inhibitor, improved the prognosis for patients with chronic myeloid leukemia (CML). We conducted efficacy and safety analyses on the basis of more than 10 years of follow‐up in patients with CML who were ...
A. Hochhaus, R. Larson, F. Guilhot, J. Radich, S. Branford, T. Hughes, M. Baccarani, M. Deininger, F. Cervantes, Satoko Fujihara, C. Ortmann, H. Menssen, H. Kantarjian, S. O’Brien, B. Druker   +14 more
semanticscholar   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source