Results 191 to 200 of about 919,731 (432)
Molecular and cytogenetic abnormalities in acute myeloid leukemia: review and case studies [PDF]
Einstein (São Paulo), 2011 Objective: To study the frequency of mutations that maylead to a good or bad prognosis, as well as their relation withthe karyotype and immunophenotype in patients with acutemyeloid leukemia. Methods: Thirty samples of patients withacute myeloid leukemia
Elvira Deolinda Rodrigues Pereira Velloso +7 more
doaj
Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining
Frontiers in Immunology, 2018 An array of phenotypically diverse myeloid cells and macrophages (MC&M) resides in the tumor microenvironment, requiring multiplexed detection systems for visualization.
Joshua Saylor +11 more
doaj +1 more source
Lipidomic approach for stratification of Acute Myeloid Leukemia patients [PDF]
arXiv, 2016 The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing structural components to build the membranes.
arxiv
Studies of Diseases of the Lymphoid and Myeloid Tissues [PDF]
, 1932 Frederic Parker +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia [PDF]
Oncotarget, Impact journals, 2018, 2019 Background: Chronic myeloid leukemia (CML) results from hematopoietic stem cell transformation by the bcr-abl chimeric oncogene, encoding a 210 kDa protein with constitutive tyrosine kinase activity. In spite of the efficiency of tyrosine kinase inhibitors (TKI; Imatinib), other strategies are explored to eliminate CML leukemia stem cells, such as ...
arxiv
Medullary Aplasia in Chronic Myeloid Leukaemia during Busulphan Therapy [PDF]
, 1957 F. G. J. Hayhoe, David L. Kok
openalex +1 more source
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
Nature, 2021 E. Yankova +24 more
semanticscholar +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source