Results 211 to 220 of about 1,067,293 (391)

An Overview of Myeloid Blast-Phase Chronic Myeloid Leukemia

Cancers
Myeloid blast-phase chronic myeloid leukemia (MBP-CML) is a rare disease with a dismal prognosis. It is twice as common as lymphoid blast-phase CML, and its prognosis is poorer. Despite the success with tyrosine kinase inhibitors in the treatment of chronic-phase CML, the same does not hold true for MBP-CML.
Gulsum E. Pamuk, Lori A. Ehrlich
openaire   +2 more sources

Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)

Advanced Materials Technologies, EarlyView.
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha, Zeqi Niu, Abha Kumari, Scott Smith, Grace Li, Kruthi Srinivasa Raju, Joseph Marvar, Thomas Leekley, Shawn Fortna, Yoon‐Tae Kang, Sunitha Nagrath   +10 more
wiley   +1 more source

Haemoglobin and red cell enzyme changes in juvenile myeloid leukaemia. [PDF]

, 1968
D. J. Weatherall, John A. Edwards, W. T. A. Donohoe   +2 more
openalex   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.

New England Journal of Medicine, 2001
B. Druker, M. Talpaz, D. Resta, B. Peng, E. Buchdunger, J. Ford, N. Lydon, H. Kantarjian, R. Capdeville, Sayuri Ohno-Jones, C. Sawyers   +10 more
semanticscholar   +1 more source

Extramedullary myeloid tumors in primary myelofibrosis [PDF]

, 1965
Philip Lieberman, Randi V. Rosvoll, Allyn B. Ley   +2 more
openalex   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Advanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu, Jingyi Liu, Wei Qin, Chengsheng Ding, Zhenghao Cai, Duohuo Shu, Hao Zhong, Yanyan Hu, Mengqin Yu, Leqi Zhou, Jianwen Li, Minhua Zheng, Bin Li, Sen Zhang, Xiao Yang, Bo Feng   +15 more
wiley   +1 more source

Chromosome Studies in Chronic Myeloid Leukaemia [PDF]

, 1965
Marshall B. Block
openalex   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Cell, 2020
Lei Zhang, Ziyi Li, Katarzyna M. Skrzypczynska, Qiao Fang, Wei Zhang, Sarah A. O’Brien, Yao He, Lynn Wang, Qiming Zhang, Aeryon Kim, Ranran Gao, Jessica Orf, Tao Wang, Deepali V. Sawant, Jiajinlong Kang, Dev Bhatt, Daniel R Lu, Chi-Ming Li, Aaron S. Rapaport, Kristy Perez, Y. Ye, Shan Wang, Xueda Hu, Xianwen Ren, W. Ouyang, Zhanlong Shen, J. Egen, Zemin Zhang, Xin Yu   +28 more
semanticscholar   +1 more source