Results 231 to 240 of about 919,731 (432)
Epitranscriptomics in myeloid malignancies
Blood Science, 2022 Li Han, Jianjun Chen, Rui Su
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner +5 more
wiley +1 more source
Desacetylmethylcolchicine in the Treatment of Myeloid Leukaemia
, 1956 A.M. Jelliffe, J. E. MacIver
openalex +2 more sources
Myeloid sarcoma on the scalp of a patient with acute myeloid leukemia
Anais Brasileiros de Dermatologia, 2019 Débora Nogueira Muniz +3 more
openaire +5 more sources
Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
Advanced Materials, EarlyView.A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura +19 more
wiley +1 more source
Hydroxyapatite Binding Peptide Lipid Nanoparticles for Biomimetic mRNA Delivery to Bone
Advanced Therapeutics, EarlyView.Targeted delivery of therapeutic mRNA to peripheral tissues, including bone, is currently challenging. In the current work, a hydroxyapatite binding peptide (HABP) is conjugated to mRNA lipid nanoparticles (LNPs). HABP‐LNPs delivered systemically are demonstrated to reduce transfection in the liver and improve transfection in the femurs of mice ...
Joshua A. Choe +6 more
wiley +1 more source
Haemoglobin and red cell enzyme changes in juvenile myeloid leukaemia. [PDF]
, 1968 D. J. Weatherall +2 more
openalex +1 more source
Advanced Science, EarlyView.This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi +18 more
wiley +1 more source
On Myeloid and Myelo-Cystic Tumours of Bone; Their Structure, Pathology, and Mode of Diagnosis [PDF]
Henry Gray
openalex +1 more source