Results 301 to 310 of about 1,067,293 (391)

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

Bacillus subtilis natto NTU-18 attenuates atherosclerosis progression by modulating peripheral immune cell alterations. [PDF]

Appl Microbiol Biotechnol
Lin JD, Ye YZ, Wang SR, Kao WY, Lee KT.
europepmc   +1 more source

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

Advanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu, Peikang Zhang, Zhen Xiong, Yufei Lan, Hui Guo, Runyuan Wu, Cunzhen Li, Hongzhe Fan, Ying Du, Xiaoxiao Zhu, Dongdong Fan, Zhonglong Wang, Yong Tian, Zusen Fan   +13 more
wiley   +1 more source

Circulating CD16-Positive Monocyte-like Myeloid-Derived Suppressor Cells and Intermediate Monocytes Associated with Clinical and Immunological Complications in Pars Planitis Patients. [PDF]

Cells
Kosmaczewska A, Przeździecka-Dołyk J, Ciszak L, Rojek-Gajda Z, Frydecka I, Turno-Kręcicka A, Misiuk-Hojło M, Pawlak E.   +7 more
europepmc   +1 more source

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

Advanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu, Hyun Sung Park, Dong‐Hoon Chae, Jae Han Park, Jiyoung Heo, Keonwoo Cho, Jiho Kim, Hyewon Lee, Sueyeon Jee, Chanwoo Kim, Soon Won Choi, Jaechul Ryu, Eun‐Hye Hur, Yunsuk Choi, Eun‐Ji Choi, Mi‐Kyung Oh, Hwa‐Yong Lee, Je‐Hwan Lee, Kyung‐Rok Yu   +18 more
wiley   +1 more source

Myeloid-Specific STAT3 Deletion Aggravates Liver Fibrosis in Mice Fed a Methionine- and Choline-Deficient Diet via Upregulation of Hepatocyte-Derived Lipocalin-2. [PDF]

Cells
Kim KE, Shin HJ, An HS, Jeong EA, Sun Y, Oh J, Park J, Lee J, Im SS, Roh GS.   +9 more
europepmc   +1 more source

Molecular Minimal Residual Disease in Acute Myeloid Leukemia

New England Journal of Medicine, 2018
M. Jongen‐Lavrencic, T. Grob, Diana Hanekamp, F. Kavelaars, A. A. Al Hinai, A. Zeilemaker, Claudia A. J. Erpelinck-Verschueren, P. Gradowska, R. Meijer, J. Cloos, B. Biemond, C. Graux, M. van Marwijk Kooy, M. Manz, T. Pabst, J. Passweg, V. Havelange, G. Ossenkoppele, M. Sanders, G. Schuurhuis, B. Löwenberg, P. Valk   +21 more
semanticscholar   +1 more source

Mobility of Carbohydrate-Containing Structures on the Surfaces Membrane and the Normal Differentiation of Myeloid Leukemic Cells to Macrophages and Granulocytes

, 1973
Michael Inbar, Hannah Ben‐Bassat, Eitan Fibach, Leo Sachs   +3 more
openalex   +1 more source

Sympathetic Activation Promotes Kidney Fibrosis in Mice via Macrophage‐Derived N2ICD‐Enriched Extracellular Vesicles

Advanced Science, EarlyView.
Norepinephrine/α2B‐adrenoceptor axis promotes the secretion of Notch2 intracellular domain (N2ICD)‐enriched extracellular vesicles (EVs) from macrophages. These EVs deliver N2ICD into fibroblasts, thereby inducing their activation. Deletion of Notch2 or α2B‐AR in macrophages disrupts N2ICD‐enriched EV formation and alleviates kidney fibrosis in mice ...
Huiwen Ren, Yayan Hou, Chengsen Mu, Yinghong Zheng, Yuanyang Wang, Shumin Guo, Lu Wang, Wenlong Shang, Zhuming Yin, Cheng Dong, Yongsheng Chang, Bin Zhou, Renjie Chai, Ying Yu, Yujun Shen   +14 more
wiley   +1 more source

Parental influence on brown trout offspring immune cell composition: An infection study with Tetracapsuloides bryosalmonae. [PDF]

PLoS One
Saura Martinez H, Delalay G, Talker S, Schmidt-Posthaus H.   +3 more
europepmc   +1 more source