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Spinal Chloroma – Herald of blast crisis in a patient with chronic myeloid leukaemia: A case report
Myeloid sarcoma or chloroma is a localised tumour characterised by extramedullary proliferation of precursor myeloid cells. Commonly occurring in association with acute myeloid leukaemia, chloroma can occasionally be seen in myeloproliferative disorders ...
Stuti Chandola +3 more
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Myeloid Sarcoma Presenting as Nasal and Orbital Mass: An Initial Manifestation of an Acute Myeloid Leukaemia [PDF]
Myeloid sarcoma is an extramedullary manifestation of Acute Myeloid Leukaemia and sometimes is the only indicator of the disease. The incidence varies between 3-9.1% of acute leukaemia cases.
Amita Jain Gupta +4 more
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Background Chronic myeloid leukaemia is characterised by genetic instability which results in additional cytogenetic aberrations that have been linked to progression to advanced phase.
Hend Attia, Dina Adel Fouad, Heba Samy
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Effects of stem cell factor on hypoxia-inducible factor 1 alpha accumulation in human acute myeloid leukaemia and LAD2 mast cells. [PDF]
Stem cell factor (SCF) is a hematopoietic growth factor that exerts its activity by signalling through the tyrosine kinase receptor known as Kit or CD117.
Bernhard F Gibbs +3 more
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Chronic myeloid leukaemia presenting as acute small bowel gangrene: A case report
Rationale: Chronic myeloid leukaemia is a myeloproliferative disorder due to clonal hyperproliferation of myeloid cells within the bone marrow. It can present both pro- and anti-thrombotic states.
Jayabal Pandiaraja, Arumugam Shalini
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Acute myeloid leukaemia (AML) is a type of cancer of the part of the bone marrow that normally makes ‘myeloid’ cells.
Sandra, Hassan, Matthew, Smith
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Congenital Acute Myeloid Leukaemia with Pseudo-Chediak-Higashi Like Granules: A Case Report [PDF]
Congenital leukaemia is a very rare entity comprising 0.8% of all childhood leukaemias. Pseudo-Chediak-Higashi Anomaly (PCHA) in acute leukaemia is a rarely described entity. However, co-existence of congenital myeloid leukaemia with PCHA is a very rare
Vandana Puri +3 more
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Childhood acute myeloid leukaemia [PDF]
SummaryAlthough acute myeloid leukaemia (AML) has long been recognized for its morphological and cytogenetic heterogeneity, recent high‐resolution genomic profiling has demonstrated a complexity even greater than previously imagined. This complexity can be seen in the number and diversity of genetic alterations, epigenetic modifications, and ...
Jeffrey E, Rubnitz, Hiroto, Inaba
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Acute myeloid leukaemia genomics [PDF]
SummaryAcute myeloid leukaemia (AML) is a biologically complex, molecularly and clinically heterogeneous disease. Despite major advances in understanding the genetic landscape of AML and its impact on the pathophysiology and biology of the disease, standard treatment options have not significantly changed during the past three decades.
Michael Medinger, Jakob R. Passweg
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Granulocytic sarcoma of the femur in a patient with acute megakaryoblastic leukaemia [PDF]
Introduction. Granulocytic sarcoma, chloroma or myeloblastoma are observed in 3% to7% of acute myeloid leukaemia and represents localized tumour composed of collection of immature leukaemic cells. It appears most frequently in patients with M2, M4 and
Čolović Milica +4 more
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