Results 111 to 120 of about 301,311 (355)

GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome

open access: yesIUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2019
Myeloid leukaemia of Down syndrome (ML‐DS) is an acute megakaryoblastic/erythroid leukaemia uniquely found in children with Down syndrome (constitutive trisomy 21).
C. Garnett   +2 more
semanticscholar   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo   +3 more
wiley   +1 more source

Chloroma of perianal region masquerading as perianal abscess

open access: yesIndian Journal of Dermatology, 2013
Chloroma, also called granulocytic sarcoma (GS) or Myeloid Sarcoma, is a rare malignant extra-medullary neoplasm of myeloid precursor cells. It is usually associated with myeloproliferative disorders but its appearance may precede the onset of leukaemia.
Rajeev Sen   +5 more
doaj   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

open access: yesAdvanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen   +2 more
wiley   +1 more source

Extramedullary Myeloid Cell Tumour Presenting As Leukaemia Cutis

open access: yesIndian Journal of Dermatology, 2002
We herewith report a case of extramedullary myeloid cell tumour presenting as leukaemia cutis for its rarity. It occurred in a 50 year old male patient who presented to us with a 40 days history of painless raised solid skin swellings over the trunk ...
Thappa Devinder Mohan   +3 more
doaj  

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

open access: yesAdvanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi   +5 more
wiley   +1 more source

Treatment of acute myeloid leukaemia [PDF]

open access: yesClinical Medicine, 2013
Acute myeloid leukaemia is a heterogeneous disease that occurs in all age groups but peaks in older age at around a median of 69-70 years where it has a frequency of 13-15/100,00/annum. With the changing demographics, the number of cases will increase in line with the older population.
openaire   +2 more sources

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