Results 271 to 280 of about 950,400 (402)

SETD2 loss of function is a recurrent event in advanced-phase chronic myeloid leukemia and contributes to genomic instability: SETD2 loss in Chronic Myeloid Leukemia. [PDF]

open access: yesClin Transl Med
Mancini M   +17 more
europepmc   +1 more source

Molecular Minimal Residual Disease in Acute Myeloid Leukemia

open access: yesNew England Journal of Medicine, 2018
M. Jongen‐Lavrencic   +21 more
semanticscholar   +1 more source

Enhancer‐dependent gene regulation in space, time, and malignancies

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum   +2 more
wiley   +1 more source

Mapping of Functional Metabolic Phenotypes in Acute Myeloid Leukemia. [PDF]

open access: yesCancer Med
Dyrstad S   +5 more
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

Long‐Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia

open access: yesNew England Journal of Medicine, 2017
A. Hochhaus   +14 more
semanticscholar   +1 more source

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