Results 271 to 280 of about 1,006,148 (403)

Androgen receptor signaling as a new target for intervention in acute myeloid leukemia. [PDF]

Blood Adv
Qian F, Sarkar D, Arner BE, Peduzzi VM, Bai Y, Ruan B, Jia B, Zheng H, Paulson RF, Prabhu KS.   +9 more
europepmc   +1 more source

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source

Chronic Myeloid Leukemia and the T315I <i>BCR::ABL1</i> Mutation. [PDF]

Int J Mol Sci
Pierro F, Stella S, Fazio M, Russo S, Massimino M, Mirabile G, Belletti D, Allegra A, Stagno F.   +8 more
europepmc   +1 more source

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Cancer Cell, 2019
Yue Huang, R. Su, Yue Sheng, Lei Dong, Ze Dong, Hongjiao Xu, Tengfeng Ni, Zijie Zhang, Tao Zhang, Chenying Li, Li Han, Zhenyun Zhu, F. Lian, Jiangbo W, Qiang-qiang Deng, Yungui Wang, M. Wunderlich, Zhi-wei Gao, Guoyu Pan, D. Zhong, Hu Zhou, Naixia Zhang, J. Gan, Hualiang Jiang, J. Mulloy, Zhijian Qian, Jianjun Chen, Cai-Guang Yang   +27 more
semanticscholar   +1 more source

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma

International Journal of Cancer, EarlyView.
What's New? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang, Ken Yamaguchi, Kohei Hamada, Yuko Hosoe, Yuka Mise, Sachiko Kitamura, Zhihong Liu, Hairong Wei, Zhenhai Gao, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Rin Mizuno, Taito Miyamoto, Junzo Hamanishi, Masaki Mandai   +15 more
wiley   +1 more source

Epigenetic dysregulation in acute myeloid leukemia. [PDF]

Semin Hematol
Schrezenmeier J, Huntly BJP.
europepmc   +1 more source

A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001 [PDF]

, 2017
Uy, Geoffrey L., Westervelt, Peter
core   +1 more source

Adapting the Fitness Criteria for Non-Intensive Treatments in Older Patients with Acute Myeloid Leukemia to the Use of Venetoclax-Hypomethylating Agents Combination—Practical Considerations from the Real-Life Experience of the Hematologists of the Rete Ematologica Lombarda [PDF]

Giuseppe Rossi, Erika Borlenghi, Patrizia Zappasodi, Federico Lussana, Massimo Bernardi, Claudia Basilico, Alfredo Molteni, Ivana Lotesoriere, Mauro Turrini, Marco Frigeni, Monica Fumagalli, Paola Cozzi, Federica Gigli, Chiara Cattaneo, Nicola Fracchiolla, Marta Riva, Gianluca Martini, Valentina Mancini, Roberto Cairoli, Elisabetta Todisco   +19 more
openalex   +1 more source

FIVE-YEAR FINAL RESULTS OF A PHASE 3 STUDY OF CPX-351 VERSUS 7+3 IN OLDER ADULTS WITH NEWLY DIAGNOSED HIGH-RISK/SECONDARY ACUTE MYELOID LEUKEMIA (AML)

, 2020
Jeffrey E. Lancet, Tsong-Shan Lin, Donna E. Hogge, Scott R. Solomon, Gary J. Schiller, Matthew J. Wieduwilt, Rubén Martín, Stefan Faderl, Yu-Chien Chang, Jörge E. Cortes   +9 more
openalex   +1 more source

Lymphoma, multiple myeloma and leukaemia incidence in regions of Belarus most heavily contaminated by the Chernobyl accident

International Journal of Cancer, EarlyView.
What's New? The 1986 Chernobyl accident led to widespread radioactive contamination across parts of Europe, with elevated childhood leukaemia rates observed in heavily affected areas of Ukraine. Data on long‐term haematological and other non‐thyroid cancer risk in the general population in heavily contaminated regions, however, remain limited.
Ljubica Zupunski, Alesia Yaumenenka, Ilya Veyalkin, Victor Minenko, Pavel Moiseyev, Joachim Schüz, Tatiana Kukhta, Sergey Trofimik, Richard Harbron, Vladimir Drozdovitch, Evgenia Ostroumova   +10 more
wiley   +1 more source