Results 301 to 310 of about 1,006,148 (403)

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

Association of the ABCB1 gene polymorphism C3435T (rs1045642) with acute myeloid leukemia: A genetic study. [PDF]

Hematol Transfus Cell Ther
Ullah R, Mazari N, Mustafa G, Hameed A, Khaliq S, Amar A, Haq FU, Khan AH, Naveed A.   +8 more
europepmc   +1 more source

Pediatric acute myeloid leukemia with t(8;21) and KIT mutation treatment with avapritinib post-stem cell transplantation: a report of four cases [PDF]

Qingwei Wang, Yixin Hu, Li Gao, Senlin Zhang, Jun Lü, Bohan Li, Jie Li, Yanhua Yao, Shengqin Cheng, Peifang Xiao, Shaoyan Hu   +10 more
openalex   +1 more source

Peripheral versus Marrow Lipidomics in Patients with Severe Aplastic Anemia: Potential Indicators for Early Immunosuppressive Treatment Response

Lipids, EarlyView.
ABSTRACT This study aimed to explore the differences of peripheral blood (PB) and bone marrow serum lipidomic profiles in severe aplastic anemia (SAA) patients and their significance in predicting earlier immunosuppressive therapy (IST) response. A cohort of 11 newly diagnosed SAA patients and 15 healthy controls were enrolled between June 2020 and ...
Zexing Sun, Yilei Hong, Yaonan Hong, Chuanao Xin, Qi Liu, Huijin Hu, Yingying Shen, Ying Chen, Shan Liu, Yiping Shen, Yuhong Zhou, Dijiong Wu   +11 more
wiley   +1 more source

Behcet's disease in a patient with chronic myeloid leukemia. [PDF]

Indian J Sex Transm Dis AIDS
Singh D, Somasundaram A, Gajula AS, Kumar S.   +3 more
europepmc   +1 more source

O tratamento da Leucemia Mielóide Crônica com mesilato de imatinibe Therapy of Chronic Myeloid Leukemia with imatinib mesylate

, 2008
Vaneuza M. Funke, D.C. Setubal, Jefferson Ruiz, Ana Paula de Azambuja, Denise H. Lima, Terezinha K. Kojo, Ricardo Pasqüini   +6 more
openalex   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Hypocellular myelodysplastic syndrome with myelofibrosis in acute myeloid leukemia transformation: A case report

, 2015
Kui Song, Xiaojun Xu, Min Li
openalex   +2 more sources

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Schlafen 12 Modulation and Targeting in Acute Myeloid Leukemia. [PDF]

Cancer Res Commun
Guillen Magaña JN, Zannikou M, Baran A, Small S, Schieber M, Schipma MJ, Bartom ET, Kocherginsky M, Saleiro D, Beauchamp EM, Eckerdt F, Platanias LC.   +11 more
europepmc   +1 more source