Results 321 to 330 of about 1,006,148 (403)

Nanoencapsulation of ferrocene incorporated thiourea and doxorubicin for treatment of acute myeloid leukemia. [PDF]

BMC Cancer
Idrees N, Rana NF, Tariq U, Fatima S, Anees M, Sabir U, Javaid S, Raza LH, Tanweer T.   +8 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Aggressive Disease and Poor Clinical Outcome in CEBPα-Mutated Acute Myeloid Leukemia Patient. [PDF]

Clin Case Rep
Alshammari AA, AlSabbagh MO, Alshehri HM, AlSwayyed AF, Alseraye FM, Peer-Zada AA.   +5 more
europepmc   +1 more source

Acute Myeloid Leukemia with NUP98: : LNP1 Fusion Mimicking Chronic Myeloid Leukemia

Turkish Journal of Hematology
Haiyang Wang, Yu Peng, Zailin Yang
openaire   +3 more sources

Leukemia in Older Adults: Global, National, and Regional Disease Burden Patterns During 1990–2019 and Forecasted Trends to 2030

Medicine Advances, EarlyView.
After analyzing the burden of leukemia in the elderly aged 60–89 years from 1990 to 2019 using the Global Burden of Disease database, we found that although the burden of chronic myeloid leukemia has decreased over the past 30 years, the burden of other types of leukemia has continued to increase to varying degrees.
Jing Wei, Qijian Feng, Ziyuan Lu
wiley   +1 more source

IL-1 signaling and inflammasomes in acute myeloid leukemia: mechanisms and therapeutic opportunities. [PDF]

Cell Mol Life Sci
Mortellaro A, Mastaglio S, Muzio M.
europepmc   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

CPX-351 and the Frontier of Nanoparticle-Based Therapeutics in Acute Myeloid Leukemia. [PDF]

Int J Mol Sci
Konstantinidis I, Tsokkou S, Keramas A, Gavriilaki E, Delis G, Papamitsou T.   +5 more
europepmc   +1 more source

Rib Ewing Sarcomas in Children and Young Adults: A Large National Retrospective Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Purpose Ewing sarcoma (ES) is the most prevalent malignant thoracic tumor in childhood and young adults. This study reports the outcome of a national cohort treated in an international prospective trial for a localized rib ES, with a long follow‐up.
Audrey Claren, Alexandre Beige, Magali Morelle, Jérôme Doyen, Cyril Lervat, Luc Ollivier, Cécile Vérité, Perrine Marec‐Bérard, Maria Jolnerovski, Anne Ducassou, Valentine Martin, Line Claude, French Multidisciplinary Working Group on Bone Primary Tumours (GROUPOS), GSF (French Sarcoma Group), GETO (Bone Tumour Study Group) and SFCE (French Society for the Fight against Childhood and Adolescent Cancer and Leukaemia)   +14 more
wiley   +1 more source

Acute Myeloid Leukemia Secondary to Radiation Therapy for Rectal Cancer: A Case Report. [PDF]

Cancer Rep (Hoboken)
Alkhaledi A, Hussaen LA, Kahla L, Sammoud B, Ghanem SG.   +4 more
europepmc   +1 more source