Results 281 to 290 of about 5,838,181 (363)

Efficacy of melflufen in multiple myeloma with mutated or deleted TP53. [PDF]

Exp Hematol Oncol
Acs K, Miettinen JJ, Sergeev P, Heckel T, Diao Y, Witt-Mulder K, Thureson M, Bischler T, Huppunen ME, Suvela M, Obermüller J, Munawar U, Slipicevic A, Bargou RC, Lehmann F, Gelius SS, Norin S, Schjesvold F, Sonneveld P, Stühmer T, Heckman CA.   +20 more
europepmc   +1 more source

DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu, Yuzhu Ma, Yueying Gao, Yao Chen, Xinyu Li, Yue Wu, Meiling Sun, Qizhao Li, Yanhong Zhao, Shuqian Xu, Shengjin Fan, Yongsheng Li, Huitao Fan   +12 more
wiley   +1 more source

Hypoxia promotes BCMA loss and a suppressive secretome thereby hindering CAR T cell therapy in multiple myeloma. [PDF]

Exp Hematol Oncol
Tu C, Van der Vreken A, Meeus F, van den Broecke L, Brons J, De Veirman K, Vanderkerken K, De Bruyne E, Breckpot K, Menu E.   +9 more
europepmc   +1 more source

T‐cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor‐Exhausted T cells to terminally exhausted T cells

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) Core Process: Persistent antigen, from TDLNs to TME, drives Tpex → Tex‐int → Tex‐term differentiation. (2) Multiomics Regulation: This fate transition is orchestrated by a co‐ordinated, multi‐layered molecular network. (3) Functional Outcome: Dysregulated signalling and surging co‐inhibitory receptors lock in proliferative arrest and functional ...
Tong Zhu, Xiaoyu Teng, Qinlian Jiao, Yidan Ren, Yunshan Wang, Maoxiao Feng   +5 more
wiley   +1 more source

Not All Bone Lesions After Breast Cancer Treatment Indicate Metastasis: A Case Report and Review of the Literature. [PDF]

Cureus
Kaakoua M, Mohamed Amine A, Ebbadi N, Boujmadi S, Sawadogo MA, Laabbar H, Hicham Y, Essadi I.   +7 more
europepmc   +1 more source

Solitary Bone Plasmacytoma of the Scapula: A Rare Localization With Remarkable Radiotherapy Outcome. [PDF]

Cureus
El Mjabber R, Alami R, El Mjabber EC, Dahbi Z, Kouhen F, Ismaili N, El Majjaoui S, Naim A.   +7 more
europepmc   +1 more source

Concomitant Transthyretin Amyloid Cardiomyopathy in Patients With Multiple Myeloma. [PDF]

JACC Case Rep
Ibrahim M, Alhusain R, Ray JC, Lyle MA, Leoni Moreno JC, Aslam N, Nativi Nicolau JN, Lin G, Sher T, Malik A.   +9 more
europepmc   +1 more source

Daratumumab monotherapy in a patient with kappa light chain multiple myeloma and decompensated cirrhosis: a case report. [PDF]

Front Oncol
Yang X, Liu Z, Zhou Y, Zhang H, Yang M, Wang H.   +5 more
europepmc   +1 more source

Rethinking surgical intervention in the multidisciplinary comprehensive management of craniocerebral metastasis in multiple myeloma. [PDF]

Medicine (Baltimore)
Shen J, Cai Y, Ouyang H, Zhong X.
europepmc   +1 more source