Results 31 to 40 of about 5,782,005 (384)
Journal of Veterinary Internal Medicine, 2021 Background Current recommendations for monitoring disease progression and response to treatment in humans with multiple myeloma include evaluation of serum paraprotein (M‐protein) concentration. Densitometry, species‐specific radial immunodiffusion (RID)
A Russell Moore +4 more
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Chronic pain in the thoracic spine as a symptom of multiple myeloma - case report
Journal of Education, Health and Sport, 2017 Multiple myeloma is a hematological cancer, characterized by the neoplastic proliferation of a single clone of plasma cell producing a monoclonal protein. The incidence of multiple myeloma increases with age. The median age ad diagnosis is between 63 and
Kamila Woźniak +4 more
doaj +3 more sources
Nature Communications, 2019 Systemic AL amyloidosis is caused by misfolding of immunoglobulin light chains and is one of the most frequently occurring forms of systemic amyloidosis.
Lynn Radamaker +8 more
doaj +1 more source
Protein tyrosine phosphatases in multiple myeloma
Cancer Letters, 2021 Many cell signaling pathways are activated or deactivated by protein tyrosine phosphorylation and dephosphorylation, catalyzed by protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), respectively. Even though PTPs are as important as PTKs in this process, their role has been neglected for a long time.
Pegah Abdollahi +2 more
openaire +4 more sources
Blood, 2017 Multiple myeloma (MM) is a plasma cell cancer that develops in the skeleton causing profound bone destruction and fractures. The bone disease is mediated by increased osteoclastic bone resorption and suppressed bone formation.
M. McDonald +33 more
semanticscholar +1 more source
Advanced Science, 2020 The roles of mitochondrial dysfunction in carcinogenesis remain largely unknown. The effects of PTEN‐induced putative kinase 1 (PINK1)‐dependent mitophagy on the pathogenesis of multiple myeloma (MM) are determined.
Shengjun Fan +11 more
doaj +1 more source
The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer. [PDF]
, 2016 Overexpression and/or hyperactivation of cyclin-dependent kinases (CDKs) are common features of most cancer types. CDKs have been shown to play important roles in tumor cell proliferation and growth by controlling cell cycle, transcription, and RNA ...
Duan, Zhenfeng +4 more
core +1 more source
Anti-BCMA Immunotoxins: Design, Production, and Preclinical Evaluation
Biomolecules, 2020 Multiple myeloma (MM) is a B-cell malignancy that is incurable for a majority of patients. B-cell maturation antigen (BCMA) is a lineage-restricted differentiation protein highly expressed in multiple myeloma cells but not in other normal tissues except ...
Tapan K. Bera
doaj +1 more source
Association of Myeloma in Patients of Chronic Kidney Disease; A Single Centered Study
Journal of Bahria University Medical and Dental College, 2023 Objective: To evaluate the frequency along with socio-demographic factors and clinical features of myeloma in patients with chronic kidney disease (CKD) presenting at a tertiary care hospital in Karachi, Pakistan.
Farzana Adnan Sheikh +4 more
doaj +1 more source
Scientific Reports, 2023 Previous studies have shown the potential of immunogenic cell death-related modalities in myeloma. The significance of IL5RA in myeloma and immunogenic cell death remains unknown.
Cong Xu +3 more
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