Results 1 to 10 of about 9,003 (164)

Burden of rare deleterious variants in WNT signaling genes among 511 myelomeningocele patients.

PLoS ONE, 2020
Genes in the noncanonical WNT signaling pathway controlling planar cell polarity have been linked to the neural tube defect myelomeningocele. We hypothesized that some genes in the WNT signaling network have a higher mutational burden in myelomeningocele
Luke Hebert, Paul Hillman, Craig Baker, Michael Brown, Allison Ashley-Koch, James E Hixson, Alanna C Morrison, Hope Northrup, Kit Sing Au   +8 more
doaj   +2 more sources

Myelomeningocele closure: A review and decision-making guidance [PDF]

JPRAS Open
Background: Myelomeningocele, the most severe neural tube defect, results from failed neural tube closure during embryogenesis, leading to herniation of the spinal cord and meninges through a vertebral defect.
Elie Ghadban, Maria Zouein, Jad Sleiman, Karl Andary, Samer Bassilios Habre   +4 more
doaj   +2 more sources

Spinal Cord Injury in Myelomeningocele: Prospects for Therapy [PDF]

Frontiers in Cellular Neuroscience, 2020
Myelomeningocele (MMC) is the most common congenital defect of the central nervous system and results in devastating and lifelong disability. In MMC, the initial failure of neural tube closure early in gestation is followed by a progressive prenatal ...
Karolina Janik, Meredith A. Manire, George M. Smith, Barbara Krynska   +3 more
doaj   +2 more sources

Changing Incidence, Outcome and Management of Myelomeningocele

Pediatric Neurology Briefs, 2009
Pediatric neurosurgeons at Children’s Memorial Hospital, Chicago, review their long-term experience and the evolution of the etiology, diagnosis and management of patients born with myelomeningocele (MM) in 1975-1979 and followed for 25 years in a multi ...
J Gordon Millichap
doaj   +2 more sources

Antenatally diagnosed myelomeningocele with associated chiari ii malformation in the third trimester. A case report [PDF]

Radiology Case Reports
Myelomeningocele, a severe form of open neural tube defect which is mostly associated with Chiari II malformation remains a cause of adverse neonatal outcomes.
Joseph Arkorful, Samuel Ackom, Emmanuel Fiagbedzi, Eric Obour, Juliana Nyamson, Ishmael Nii Ofori   +5 more
doaj   +2 more sources

Dental Management of Child with Myelomeningocele Associated with Type II Arnold-Chiari Malformation: Case Report and Review of Literature. [PDF]

Int J Clin Pediatr Dent
Padmanabhan MY.
europepmc   +2 more sources

The Mechanism of Bladder Injury in Fetal Rats With Myelomeningocele

Frontiers in Neurology, 2022
BackgroundBladder dysfunction has been implicated as a major cause of progressive renal failure in children with neurogenic bladder. However, its pathogenesis remains unclear.
Ying Liu, Li Chen, Yunli Bi, Jian Shen, Hong Chen, Yujie Ma   +5 more
doaj   +1 more source

Myelomeningocele defect reconstruction with keystone flaps: vascular rationale for the design and operative technique

Archives of Plastic Surgery, 2021
Background Myelomeningocele is a frequently seen condition at tertiary care hospitals. Its treatment involves a variety of plastic reconstructive techniques. Herein, we present a series of myelomeningocele patients treated using keystone flaps.
Beatriz Hatsue Kushida-Contreras, Miguel Angel Gaxiola-García   +1 more
doaj   +1 more source

Congenital cardiac anomalies in myelomeningocele patients [PDF]

Acta Medica Academica, 2014
Objective. Myelomeningocele may be isolated but more frequently is associated with other anomalies. Congenital heart disease occurs with different incidence rate in myelomeningocele which is observed more frequently with skeletal malformations.
Iman Moeini Naghani, Taraneh Hashemi Zonouz, Shima Shahjouei, Amir Azar Homayoun, Farideh Nejat, Mostafa El Khashab   +5 more
doaj   +1 more source

Folate metabolism gene 5,10-methylenetetrahydrofolate reductase (MTHFR) is associated with ADHD in myelomeningocele patients.

PLoS ONE, 2012
The objective of this study was to examine the relation between the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene and behaviors related to attention- deficit/hyperactivity disorder (ADHD) in individuals with myelomeningocele.
Catherine J Spellicy, Hope Northrup, Jack M Fletcher, Paul T Cirino, Maureen Dennis, Alanna C Morrison, Carla A Martinez, Kit Sing Au   +7 more
doaj   +1 more source