Results 371 to 380 of about 146,491 (388)

Dispersibility-Dependent Biodegradation of Graphene Oxide by Myeloperoxidase.

Small, 2015
Understanding human health risk associated with the rapidly emerging graphene-based nanomaterials represents a great challenge because of the diversity of applications and the wide range of possible ways of exposure to this type of materials. Herein, the
Rajendra Kurapati, J. Russier, M. Squillaci, E. Treossi, C. Ménard‐Moyon, A. E. Del Rio-Castillo, E. Vázquez, P. Samorí, V. Palermo, A. Bianco   +9 more
semanticscholar   +1 more source

Interaction of myeloperoxidase with diclofenac

Biochemical Pharmacology, 1990
The chlorinating activity of myeloperoxidase, isolated from human polymorphonuclear neutrophils, was inhibited by the non-steroidal anti-inflammatory drug diclofenac (Voltaren). The concentration of diclofenac needed for 50% inhibition was 20 microM, a value comparable with IC50 values found for other drugs.
N.M.M. Nibbering, Ron Wever, K.W.M. Zuurbier, A.R.J. Bakkenist, R.H. Fokkens, Anton O. Muijsers   +5 more
openaire   +3 more sources

Reactions of Superoxide with Myeloperoxidase

Biochemistry, 2007
When neutrophils ingest bacteria, they discharge superoxide and myeloperoxidase into phagosomes. Both are essential for killing of the phagocytosed micro-organisms. It is generally accepted that superoxide is a precursor of hydrogen peroxide which myeloperoxidase uses to oxidize chloride to hypochlorous acid. Previously, we demonstrated that superoxide
Mark B. Hampton, Robert F. Anderson, Christine C. Winterbourn, Anthony J. Kettle   +3 more
openaire   +3 more sources

Candidacidal activity of myeloperoxidase: Characterization of myeloperoxidase-yeast complex formation

Biochemical and Biophysical Research Communications, 1988
We have previously demonstrated the ability of human neutrophil myeloperoxidase to bind to cell wall mannan polysaccharide isolated from Candida albicans. This binding capacity provides for association of the enzyme with target yeast which is essential for efficient candidacidal activity.
Clifford D. Wright, Robert D. Nelson
openaire   +3 more sources

Interaction between myeloperoxidase and antibodies against myeloperoxidase measured by chemiluminescence [PDF]

Journal of Bioluminescence and Chemiluminescence, 1993
AbstractWe investigated interaction between antibodies directed against myeloperoxidase (anti‐MPO) and myeloperoxidase (MPO) with chemiluminescence. Whole serum diluted 1/10 containing circulating anti‐MPO antibodies as well as serum from normal blood donors inhibited myeloperoxidase (MPO) enzyme activity when incubated with 1.42 m̈g MPO.
openaire   +2 more sources

Myeloperoxidase has Directly-opposed Effects on Nitration Reaction--Study on Myeloperoxidase-deficient Patient and Myeloperoxidase-knockout Mice

Free Radical Research, 2003
Myeloperoxidase (MPO) catalyzes a nitration reaction to form nitrotyrosine in the presence of high nitrite, the metabolite of NO. Human leukocyte was shown to cause phenolic nitration using released MPO as a catalyst in the presence of nitrite. It opposes our previous finding that inhibition of MPO was essential for phenol nitration in human leukocyte ...
Yosuke Kameoka, Fumikazu Kohi, Akiko Ishida-Okawara, Hiroe Nakazawa, Kohji Ichimori, Naoto Fukuyama, Hideki Koyama, Yasuaki Aratani, Kazuo Suzuki, Shunya Takizawa   +9 more
openaire   +3 more sources

Myeloperoxidase of the leukocyte of normal blood. I. Reaction of myeloperoxidase with hydrogen peroxide

Biochimica et Biophysica Acta (BBA) - Enzymology, 1970
Abstract Myeloperoxidase (donor:H2O2 oxidoreductase, EC 1.11.1.7; also known as verdoperoxidase, neutrophil peroxidase) prepared from normal peripheral blood leukocyte of pig reacted with hydrogen peroxide to form three compounds which correspond to Compounds I, II and III, well characterized in the reaction between hydrogen peroxide and peroxidases ...
Takeshi Odajima, Isao Yamazaki
openaire   +3 more sources

Myeloperoxidase: Its role for host defense, inflammation, and neutrophil function.

Archives of Biochemistry and Biophysics, 2018
Y. Aratani
semanticscholar   +1 more source

Myeloperoxidase - A bridge linking inflammation and oxidative stress with cardiovascular disease.

Clinica chimica acta; international journal of clinical chemistry, 2019
G. Ndrepepa
semanticscholar   +1 more source

Myeloperoxidase in the inflamed colon: A novel target for treating inflammatory bowel disease.

Archives of Biochemistry and Biophysics, 2018
B. Chami, N. Martin, J. Dennis, P. Witting   +3 more
semanticscholar   +1 more source