Results 101 to 110 of about 39,467 (264)
Cell Biology International, Volume 49, Issue 10, Page 1262-1273, October 2025.ABSTRACT Calreticulin is a multifunctional protein found in the endoplasmic reticulum lumen that is important for calcium homeostasis and glycoprotein folding. Mutations in exon 9 of the CALR gene are the second most common genetic cause of myeloproliferative neoplasms.
Mifra Faiz +2 more
wiley +1 more source
Acute Lymphoblastic Leukemia Arising in CALR Mutated Essential Thrombocythemia
Case Reports in Hematology, 2016 The development of acute lymphoblastic leukemia in an existing myeloproliferative neoplasm is rare with historical cases unable to differentiate between concomitant malignancies or leukemic transformation.
Stephen E. Langabeer +8 more
doaj +1 more source
To the problem of thrombus-hemorrhagic complications in chronic myeloproliferative neoplasias. Complicated diagnosis. Clinical case conference [PDF]
Medičnì Perspektivi, 2015 Disturbances in the system of he¬mostasis and vascular complications is the topical clinical problem, requiring profound study with the development of treatment and prophylaxis algorithm.
Nikolayenko-Kamyshova T.P.
doaj
Сучасні класифікації хронічних мієлопроліферативних захворювань: стандарти та тенденції вдосконалення [PDF]
, 2008 In work modern signs on classification of chronic myeloproliferative diseases are presented. The role oncogene in pathogenesis myeloproliferative diseases, their basic influence on development of pathology is covered.
Лисенко, Д.А.
core
The Molecular Biology of Myeloproliferative Disorders [PDF]
Cancer Cell, 2010 The myeloproliferative disorders (MPDs) are a spectrum of clonal disorders of the hematopoietic system. The discovery of activating mutations of the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and primary myelofibrosis has lead to in vitro and animal model studies that promise to lead to therapeutic advances.
openaire +3 more sources
Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms [PDF]
, 2015 Myeloproliferative neoplasms (MPN) are a diverse group of chronic hematological disorders that involve unregulated clonal proliferation of white blood cells.
Kapur, Reuben, Pandey, Ruchi
core +1 more source
Cancer in pregnancy: FIGO Best practice advice and narrative review
International Journal of Gynecology &Obstetrics, Volume 171, Issue 1, Page 131-151, October 2025.Abstract Cancer during pregnancy is relatively rare. The incidence is underestimated due to the lack of international registries covering both high‐income and low‐ and middle‐income countries, and is expected to rise with increasing maternal age and increasing global adoption of cell‐free DNA testing for aneuploidy.
Surabhi Nanda +29 more
wiley +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2008 Síndromes mieloproliferativas (SMPs) são doenças hematopoéticas de origem clonal que apresentam amplificação de uma ou mais linhagens mielóides. Policitemia vera (PV), trombocitemia essencial (TE), mielofibrose idiopática (MF) e leucemia mielóide crônica
Bárbara C. R. Monte-Mór +1 more
doaj +1 more source
eJHaem, Volume 6, Issue 5, October 2025.ABSTRACT Background The emergence of JAK2‐mutated myeloproliferative neoplasms (MPNs) after remission from acute myeloid leukaemia (AML) is exceedingly rare. Case Description This case series describes two patients who developed JAK2‐mutated MPNs years after achieving AML remission, each retaining persistent TET2 and SRSF2 mutations while losing AML ...
Mark Anthony Turingan +5 more
wiley +1 more source
Myeloproliferative disorders and its associated mutations
Research in Molecular Medicine, 2014 Myeloproliferative Neoplasm (MPN) are a clonal disorder in hematopoietic stem cells (HSC). MPN is categorized to 8 subclasses, including chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocytopenia (ET), primary myelofibrosis (PMF),
Kaveh Tari +6 more
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