Results 121 to 130 of about 60,444 (298)
• To evaluate the efficacy and safety of a radiosensitizer: sodium glycididazole (CMNa) combined with definitive concurrent chemoradiotherapy (CCRT). • CMNa plus CCRT improved the ORR of patients compared with CCRT alone without causing significant side effects. OPN might be a predictor of the benefit of ORR of CMNa.
Xiaoling Li +11 more
wiley +1 more source
Adverse drug reactions have a direct impact on the treatment effect and quality of life of patients with malignant tumors. Research has found that moxibustion can effectively relieve the chemotherapy-induced adverse drug reactions.
YA Liu (严柳), GAO Yaqian (高雅倩)
doaj +1 more source
Background Ginsenoside Re (Re) is one of the major components of Panax ginseng Meyer. Ginsenoside Rk3 (Rk3) is a secondary metabolite of Re. The aim of this study was to investigate and compare the effects and underlying mechanisms of Re and Rk3 on ...
Jiahong Han +8 more
semanticscholar +1 more source
Construction and validation of a predictive model for the risk of myelosuppression after first-line chemotherapy in patients with advanced colorectal cancer [PDF]
Objective To investigate the risk factors influencing the incidence of chemotherapy-induced myelosuppression (CIM) following first-line chemotherapy in patients with moderately advanced colorectal cancer (CRC), and to develop and validate a nomogram to ...
WANG Xuexing +3 more
doaj +1 more source
Pharmacometabolomics has been already successfully used in toxicity prediction for one specific adverse effect. However in clinical practice, two or more different toxicities are always accompanied with each other, which puts forward new challenges for ...
Yi-qiao Gao +7 more
semanticscholar +1 more source
Anatomical Diagram: It shows a cross‐section of the pelvic area highlighting the rectum and lateral lymph nodes, which are the focal points of the treatment strategy discussed in the paper. Flowchart: It outlines the treatment process from preoperative synchronized radiation therapy to the subsequent surgical procedures, illustrating the sequence of ...
Xinjue Shi +7 more
wiley +1 more source
Mathematical models for cytarabine-derived myelosuppression in acute myeloid leukaemia
We investigate the personalisation and prediction accuracy of mathematical models for white blood cell (WBC) count dynamics during consolidation treatment using intermediate or high-dose cytarabine (Ara-C) in acute myeloid leukaemia (AML).
Felix Jost +4 more
semanticscholar +1 more source
Summary of the Asia Pacific Advanced Prostate Cancer Symposium 2025, showing disciplines and diversity of participants, discussion topics (high‐risk localized/locally advanced prostate cancer; PSA persistence and recurrence; radioligand therapy; genetics and genomics; bone protection and other aspects of supportive care), key themes, and high‐level ...
Edmund Chiong +28 more
wiley +1 more source
Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments [PDF]
Purpose The blood brain barrier compromises glioblastoma chemotherapy. However high blood concentrations of lipophilic, alkylating drugs result in brain uptake, but cause myelosuppression.
Benattayallah, A +12 more
core
Curcumin activates DNA repair pathway in bone marrow to improve carboplatin-induced myelosuppression
Carboplatin, a second-generation platinum agent, has been used as a cancer therapy for decades and exhibits strong anti-tumor activity. However, the wide application of carboplatin is largely limited due to its side effects, especially myelosuppression ...
Xiao Chen +6 more
semanticscholar +1 more source

