Results 261 to 270 of about 60,444 (298)

Ameliorative effects of ginsenosides on myelosuppression induced by chemotherapy or radiotherapy.

Journal of Ethnopharmacology, 2020
BACKGROUND and ethnopharmacological relevance: As the major side effect of radiotherapy or chemotherapy, myelosuppression usually leads to anemia, hemorrhage, immunosuppression, and even fatal infections, which may discontinue the process of cancer ...
Mengjiao He, Na Wang, Wenxiu Zheng, Xiaoqing Cai, Dongmei Qi, Yongqing Zhang, Chunchao Han   +6 more
semanticscholar   +1 more source

Mechanistic Models for Myelosuppression

Investigational New Drugs, 2003
As myelosuppression is the dose-limiting toxicity for most chemotherapeutic drugs, modelers attempt to find relationships between drug and toxicity to optimize treatment. Mechanistic models, i.e. models based on physiology and pharmacology, are preferable over empirical models, as prior information can be utilized and as they generally are more ...
Lena E, Friberg, Mats O, Karlsson
openaire   +2 more sources

Possible involvement of TRPM2 activation in 5-fluorouracil-induced myelosuppression in mice.

European Journal of Pharmacology, 2020
Transient receptor potential melastatin 2 (TRPM2) is an oxidative stress-sensitive Ca2+-permeable channel. The activation of TRPM2 by H2O2 causes cell death in various types of cells.
Masaaki Ishibashi, M. Ishii, Shinichiro Yamamoto, Y. Mori, S. Shimizu   +4 more
semanticscholar   +1 more source

Carboplatin-Induced Myelosuppression As Related To Body Weight In Dogs.

Veterinary and Comparative Oncology, 2020
Smaller dogs are known to have an increased risk of chemotherapy-induced myelosuppression for doxorubicin, mitoxantrone, and melphalan. This retrospective study aimed to determine if dogs
Calli Coffee, J. Roush, M. L. Higginbotham   +2 more
semanticscholar   +1 more source

Myelosuppression in Legionnaires' Disease

Archives of Internal Medicine, 1982
• A patient undergoing examination for moderately severe renal insufficiency had fulminant five-lobed pneumonia caused by Legionella pneumophila . Her clinical course was complicated by granulocytopenia. Bone marrow aspiration showed notable inhibition of myelopoiesis, involving all stages of maturation.
B E, Johnson, S R, Lynch, C H, Park
openaire   +3 more sources

Study of the Effects and Mechanisms of Ginsenoside Compound K on Myelosuppression.

Journal of Agricultural and Food Chemistry, 2019
Ginsenoside compound K (CK) is not a ginsenoside that naturally exists in Panax ginseng Meyer. However, CK is a major metabolite of ginsenoside Rb1, Rb2, or Rc in the intestine under the effects of bacteria.
Jiahong Han, Yu Wang, Enbo Cai, Lianxue Zhang, Yan Zhao, Nian-zheng Sun, Xiaoman Zheng, Siqi Wang   +7 more
semanticscholar   +1 more source

Pharmacological and transcriptome profiling analyses of Fufang E'jiao Jiang during chemotherapy-induced myelosuppression in mice.

Journal of Ethnopharmacology, 2019
ETHNOPHARMACOLOGICAL RELEVANCE Fufang E'jiao Jiang (FEJ), a famous traditional Chinese medicine formula from "Liangyi Ointment", consists of five crude drugs, Colla corii asini, Radix Ginseng Rubra, Radix Rehmanniae Preparata, Codonopsis pilosula, and ...
Yan Zhang, T. Ye, Zhuping Hong, Shuqing Gong, Xiangshan Zhou, Haibin Liu, Jingyang Qian, Hai-bin Qu   +7 more
semanticscholar   +1 more source

Drug-Induced Myelosuppression

Drug Safety, 2003
Myelosuppression is a common and anticipated adverse effect of cytotoxic chemotherapy. It is a potential but rare idiosyncratic effect with any other drug, but there is a recognised association with a number of higher-risk agents which justify additional vigilance.
openaire   +2 more sources

Home enteral nutrition may prevent myelosuppression of patients with nasopharyngeal carcinoma treated by concurrent chemoradiotherapy

Head and Neck, 2019
The aim of this study is to assess the effect of home enteral nutrition (HEN) on the myelosuppression of patients with nasopharyngeal cancer (NPC) during the course of concurrent chemoradiotherapy (CCRT).
Xuemei Li, Jidan Zhou, C. Chu, Qian You, R. Zhong, Zhiyong Rao, Wen Hu   +6 more
semanticscholar   +1 more source

Supportive Care: Myelosuppression

2005
The success of aggressive, curative anticancer therapies in pediatric oncology is possible only with intensive supportive-care measures. For example, antimicrobial prophylaxis can reduce infection rates in children undergoing myelosuppressive chemotherapy.
Nidra I. Rodriguez Cruz, Renee M. Madden, Craig A. Mullen   +2 more
openaire   +1 more source