Results 141 to 150 of about 1,289,832 (353)

Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction.

New England Journal of Medicine, 1998
BACKGROUND Type 2 (non-insulin-dependent) diabetes is associated with a marked increase in the risk of coronary heart disease. It has been debated whether patients with diabetes who have not had myocardial infarctions should be treated as aggressively ...
S. Haffner, S. Lehto, T. Rönnemaa, K. Pyörälä, M. Laakso   +4 more
semanticscholar   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

Pre-Hospital Management of Acute Myocardial Infarction Using Tele-Electrocardiography System [PDF]

arXiv, 2018
A comprehensive survey revealed that many patients of Acute Myocardial Infarction reach to the hospital so late to deliver an effective treatment. This leads to poor treatment outcome which increases the mortality rates. Multiple reasons such as lack of diagnostic facilities in the rural health care centers and absence of cardiologists in Emergency ...
arxiv  

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Angiogenesis and Vasculogenesis at 7-Day of Reperfused Acute Myocardial Infarction [PDF]

, 2008
Objectives This study is to investigate the angiogenesis and vasculogenesis at the first week of reperfused acute myocardial infarction (AMI). Methods 16 of mini-swines (20 to 30 Kg) were randomly assigned to the sham ...
Qing-zhi Wang, Sheng Kang, Wei-feng Shen, Yi Tian, Yu-tong Cheng, Yue L. I. Li, Yue-jin Yang   +6 more
core   +1 more source

Recognition of fibrotic infarct density by the pattern of local systolic-diastolic myocardial electrical impedance [PDF]

, 2016
Myocardial electrical impedance is a biophysical property of the heart that is influenced by the intrinsic structural characteristics of the tissue. Therefore, the structural derangements elicited in a chronic myocardial infarction should cause specific ...
Amoros Figueras, Gerard, Bragós Bardia, Ramon, Cinca Cuscullola, Juan Maria, García Sánchez, Tomás, Jorge, Esther, Rosell Ferrer, Francisco Javier   +5 more
core   +2 more sources

Myocardial ischemia and infarction

Journal of the American College of Cardiology, 2004
Atherosclerotic heart disease is the leading cause of death in developed nations. Manifestations include myocardial ischemia or infarction. In addition, some patients develop cardiovascular insufficiency, with the additional risk of systemic ischemia.
openaire   +3 more sources

Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.

New England Journal of Medicine, 2019
BACKGROUND Data regarding high-sensitivity troponin concentrations in patients presenting to the emergency department with symptoms suggestive of myocardial infarction may be useful in determining the probability of myocardial infarction and subsequent ...
J. Neumann, R. Twerenbold, F. Ojeda, N. Sörensen, A. Chapman, Anoop S. V. Shah, A. Anand, J. Boeddinghaus, T. Nestelberger, P. Badertscher, A. Mokhtari, J. Pickering, R. Troughton, J. Greenslade, W. Parsonage, M. Mueller-Hennessen, T. Gori, T. Jernberg, Niall Morris, C. Liebetrau, C. Hamm, H. Katus, T. Münzel, U. Landmesser, V. Salomaa, L. Iacoviello, M. Ferrario, S. Giampaoli, F. Kee, B. Thorand, A. Peters, R. Borchini, T. Jørgensen, S. Söderberg, S. Sans, H. Tunstall-Pedoe, K. Kuulasmaa, T. Renné, K. Lackner, A. Worster, R. Body, U. Ekelund, P. Kavsak, T. Keller, B. Lindahl, P. Wild, E. Giannitsis, M. Than, L. Cullen, N. Mills, C. Mueller, T. Zeller, D. Westermann, S. Blankenberg   +53 more
semanticscholar   +1 more source

Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly

Advanced Science, EarlyView.
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao, Siqi Chen, Nian Cao, Wenjun Wu, Guangqin Liu, Jun Gao, Jiayi Chen, Ting Li, Dingyi Lu, Lingmin Zeng, Haizhen Zhu, Weina Zhang, Qing Xia, Teng Li, Tao Zhou, Xue‐Min Zhang, Ai‐Ling Li, Xin Pan   +17 more
wiley   +1 more source

Beyond the ISCHEMIA Trial: Revascularization for Stable Ischemic Heart Disease in Patients With High‐Risk Coronary Anatomical Features

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Brian A. Bergmark, David A. Morrow
doaj   +1 more source